Tang, 2004: Overview of all reported HSP-SPAST patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
♀
|
A
|
CHN
|
2
|
47
|
No
|
Cognitive impairment subdomain
Spasticity, lower limb Cognitive impairment Pes cavus Abnormality of the bladder Show more (+2) |
n.a.
|
|
No
|
♂
|
A
|
CHN
|
40
|
60
|
No
|
Spasticity, lower limb
Hyperreflexia in upper limbs Walking aids Impaired vibratory sensation Pes cavus Show more (+2) |
n.a.
|
|
Yes
|
♂
|
A
|
CHN
|
15
|
34
|
No
|
-Pure or uncomplicated
Hyperreflexia in upper limbs Spasticity, lower limb |
n.a.
|
|
No
|
♂
|
A
|
CHN
|
2
|
39
|
No
|
-Lower limb amyotrophy
Cognitive impairment subdomain Spasticity, lower limb Hyperreflexia in upper limbs Ataxia, limb Cognitive impairment Walking aids Abnormality of the bladder Show more (+5) |
n.a.
|
|
Yes
|
♂
|
A
|
CHN
|
2
|
14
|
No
|
Abnormality of the bladder
Impaired vibratory sensation Spasticity, lower limb |
n.a.
|
|
No
|
♂
|
A
|
CHN
|
46
|
67
|
No
|
Impaired vibratory sensation
Wheelchair -Pure or uncomplicated Hyperreflexia in upper limbs Spasticity, lower limb Abnormality of the bladder Show more (+3) |
n.a.
|
|
Yes
|
♂
|
A
|
CHN
|
35
|
50
|
No
|
Impaired vibratory sensation
Spasticity, lower limb Cognitive impairment Abnormality of the bladder Show more (+1) |
n.a.
|
|
Yes
|
♂
|
A
|
CHN
|
29
|
36
|
No
|
Spasticity, lower limb
Pes cavus Hyperreflexia in upper limbs Impaired vibratory sensation Show more (+1) |
n.a.
|
|
No
|
♂
|
A
|
CHN
|
19
|
59
|
No
|
n.a.
|
||
No
|
♀
|
A
|
CHN
|
30
|
35
|
No
|
Spasticity, lower limb
Abnormality of the bladder -Pure or uncomplicated |
n.a.
|