Hatano, 2004: Overview of all reported PARK-PINK1 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♀
|
A
|
JPN
|
33
|
41
|
No
|
Dyskinesia
Postural tremor Psychotic sign/sympt. Parkinsonism NMS parkinsonism Bradykinesia Motor fluctuations Tremor (any or unspecified) -Motor Postural instability Dystonia Rigidity Hyperreflexia Show more (+10) |
n.a.
|
|
No
|
♀
|
n.a.
|
TWN
|
19
|
43
|
Yes
|
-Motor
Tremor (any or unspecified) Sleep benefit Dyskinesia Bradykinesia Parkinsonism Motor fluctuations Tremor at rest Rigidity Show more (+6) |
n.a.
|
|
No
|
♂
|
O
|
ISR
|
33
|
52
|
Yes
|
Cognitive decline
Parkinsonism Anxiety NMS parkinsonism -Motor Postural instability Psychotic sign/sympt. Dyskinesia Sleep disorder Depression Bradykinesia Rigidity Motor fluctuations Show more (+10) |
Anxiety
Depression |
|
No
|
♀
|
n.a.
|
PHL
|
27
|
50
|
Yes
|
Parkinsonism
Tremor at rest -Motor Dyskinesia Postural instability Motor fluctuations Tremor (any or unspecified) Bradykinesia Show more (+5) |
n.a.
|
|
Yes
|
♀
|
n.a.
|
TWN
|
18
|
40
|
Yes
|
Tremor at rest
Dyskinesia Tremor (any or unspecified) -Motor Motor fluctuations Sleep benefit Parkinsonism Bradykinesia Dystonia Rigidity Show more (+7) |
n.a.
|
|
Yes
|
♂
|
A
|
JPN
|
30
|
47
|
Yes
|
Rigidity
Postural instability -Motor Dyskinesia Hyperreflexia Bradykinesia Motor fluctuations Parkinsonism Show more (+5) |
n.a.
|
|
Yes
|
♀
|
A
|
JPN
|
23
|
38
|
No
|
NMS parkinsonism
Motor fluctuations Parkinsonism Tremor (any or unspecified) -Motor Bradykinesia Postural instability Psychotic sign/sympt. Hyperreflexia Sleep benefit Tremor at rest Rigidity Show more (+9) |
n.a.
|
|
No
|
♀
|
n.a.
|
PHL
|
32
|
51
|
Yes
|
Bradykinesia
Parkinsonism Motor fluctuations Rigidity Tremor (any or unspecified) Postural instability Tremor at rest -Motor Show more (+5) |
n.a.
|
|
Yes
|
♀
|
n.a.
|
PHL
|
27
|
45
|
Yes
|
Tremor (any or unspecified)
Motor fluctuations Parkinsonism Tremor at rest Rigidity Dyskinesia Bradykinesia -Motor Postural instability Show more (+6) |
n.a.
|
|
Yes
|
♂
|
O
|
ISR
|
25
|
47
|
Yes
|
Dyskinesia
Anxiety Hyperreflexia Sleep benefit Rigidity NMS parkinsonism Parkinsonism Postural instability -Motor Depression Motor fluctuations Bradykinesia Cognitive decline Psychotic sign/sympt. Show more (+11) |
Anxiety
Depression |