Hatano, 2004: Overview of all reported PARK-PINK1 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♀
|
A
|
JPN
|
33
|
41
|
No
|
NMS parkinsonism
Motor fluctuations Dyskinesia Rigidity Tremor (any or unspecified) Postural tremor Bradykinesia -Motor Psychotic sign/sympt. Dystonia Postural instability Hyperreflexia Parkinsonism Show more (+10) |
n.a.
|
|
No
|
♀
|
n.a.
|
TWN
|
19
|
43
|
Yes
|
Motor fluctuations
Tremor at rest Rigidity Dyskinesia Parkinsonism Sleep benefit Tremor (any or unspecified) Bradykinesia -Motor Show more (+6) |
n.a.
|
|
No
|
♂
|
O
|
ISR
|
33
|
52
|
Yes
|
Motor fluctuations
Depression Sleep disorder Bradykinesia NMS parkinsonism Psychotic sign/sympt. -Motor Cognitive decline Parkinsonism Rigidity Postural instability Dyskinesia Anxiety Show more (+10) |
Depression
Anxiety |
|
No
|
♀
|
n.a.
|
PHL
|
27
|
50
|
Yes
|
Bradykinesia
-Motor Tremor at rest Motor fluctuations Tremor (any or unspecified) Parkinsonism Dyskinesia Postural instability Show more (+5) |
n.a.
|
|
Yes
|
♀
|
n.a.
|
TWN
|
18
|
40
|
Yes
|
Sleep benefit
-Motor Tremor (any or unspecified) Rigidity Dystonia Motor fluctuations Dyskinesia Tremor at rest Parkinsonism Bradykinesia Show more (+7) |
n.a.
|
|
Yes
|
♂
|
A
|
JPN
|
30
|
47
|
Yes
|
Motor fluctuations
Bradykinesia Rigidity Postural instability Hyperreflexia Parkinsonism Dyskinesia -Motor Show more (+5) |
n.a.
|
|
Yes
|
♀
|
A
|
JPN
|
23
|
38
|
No
|
-Motor
Sleep benefit Bradykinesia Hyperreflexia Tremor (any or unspecified) Tremor at rest Motor fluctuations Parkinsonism Psychotic sign/sympt. Postural instability Rigidity NMS parkinsonism Show more (+9) |
n.a.
|
|
No
|
♀
|
n.a.
|
PHL
|
32
|
51
|
Yes
|
Rigidity
Bradykinesia Motor fluctuations Tremor (any or unspecified) -Motor Postural instability Tremor at rest Parkinsonism Show more (+5) |
n.a.
|
|
Yes
|
♀
|
n.a.
|
PHL
|
27
|
45
|
Yes
|
Parkinsonism
Bradykinesia Postural instability Tremor at rest Rigidity Dyskinesia Motor fluctuations -Motor Tremor (any or unspecified) Show more (+6) |
n.a.
|
|
Yes
|
♂
|
O
|
ISR
|
25
|
47
|
Yes
|
Bradykinesia
Postural instability Parkinsonism Rigidity Dyskinesia NMS parkinsonism Anxiety Hyperreflexia Psychotic sign/sympt. Motor fluctuations Cognitive decline -Motor Sleep benefit Depression Show more (+11) |
Anxiety
Depression |