Hatano, 2004: Overview of all reported PARK-PINK1 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♀
|
A
|
JPN
|
33
|
41
|
No
|
Psychotic sign/sympt.
Postural tremor Dystonia Tremor (any or unspecified) -Motor NMS parkinsonism Bradykinesia Hyperreflexia Motor fluctuations Postural instability Parkinsonism Dyskinesia Rigidity Show more (+10) |
n.a.
|
|
No
|
♀
|
n.a.
|
TWN
|
19
|
43
|
Yes
|
Parkinsonism
Tremor at rest Rigidity Dyskinesia Motor fluctuations Tremor (any or unspecified) -Motor Sleep benefit Bradykinesia Show more (+6) |
n.a.
|
|
No
|
♂
|
O
|
ISR
|
33
|
52
|
Yes
|
Postural instability
-Motor Psychotic sign/sympt. Motor fluctuations NMS parkinsonism Depression Rigidity Anxiety Cognitive decline Parkinsonism Dyskinesia Bradykinesia Sleep disorder Show more (+10) |
Depression
Anxiety |
|
No
|
♀
|
n.a.
|
PHL
|
27
|
50
|
Yes
|
Dyskinesia
Tremor at rest Bradykinesia Parkinsonism Postural instability -Motor Motor fluctuations Tremor (any or unspecified) Show more (+5) |
n.a.
|
|
Yes
|
♀
|
n.a.
|
TWN
|
18
|
40
|
Yes
|
-Motor
Bradykinesia Dystonia Tremor at rest Dyskinesia Tremor (any or unspecified) Motor fluctuations Parkinsonism Rigidity Sleep benefit Show more (+7) |
n.a.
|
|
Yes
|
♂
|
A
|
JPN
|
30
|
47
|
Yes
|
Postural instability
Motor fluctuations -Motor Dyskinesia Hyperreflexia Bradykinesia Parkinsonism Rigidity Show more (+5) |
n.a.
|
|
Yes
|
♀
|
A
|
JPN
|
23
|
38
|
No
|
Bradykinesia
NMS parkinsonism Postural instability Sleep benefit Tremor (any or unspecified) -Motor Motor fluctuations Rigidity Psychotic sign/sympt. Tremor at rest Parkinsonism Hyperreflexia Show more (+9) |
n.a.
|
|
No
|
♀
|
n.a.
|
PHL
|
32
|
51
|
Yes
|
Bradykinesia
Postural instability Tremor at rest Motor fluctuations Rigidity Parkinsonism -Motor Tremor (any or unspecified) Show more (+5) |
n.a.
|
|
Yes
|
♀
|
n.a.
|
PHL
|
27
|
45
|
Yes
|
Motor fluctuations
Rigidity Bradykinesia Dyskinesia Parkinsonism -Motor Tremor at rest Tremor (any or unspecified) Postural instability Show more (+6) |
n.a.
|
|
Yes
|
♂
|
O
|
ISR
|
25
|
47
|
Yes
|
Cognitive decline
Psychotic sign/sympt. Rigidity Parkinsonism Bradykinesia -Motor Motor fluctuations Dyskinesia NMS parkinsonism Hyperreflexia Depression Postural instability Sleep benefit Anxiety Show more (+11) |
Depression
Anxiety |