Hatano, 2004: Overview of all reported PARK-PINK1 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♀
|
A
|
JPN
|
33
|
41
|
No
|
Psychotic sign/sympt.
Rigidity Dystonia Tremor (any or unspecified) Bradykinesia Dyskinesia -Motor NMS parkinsonism Hyperreflexia Postural tremor Postural instability Motor fluctuations Parkinsonism Show more (+10) |
n.a.
|
|
No
|
♀
|
n.a.
|
TWN
|
19
|
43
|
Yes
|
Parkinsonism
Rigidity Motor fluctuations Sleep benefit Tremor at rest Dyskinesia -Motor Tremor (any or unspecified) Bradykinesia Show more (+6) |
n.a.
|
|
No
|
♂
|
O
|
ISR
|
33
|
52
|
Yes
|
Psychotic sign/sympt.
Parkinsonism Rigidity -Motor Motor fluctuations Cognitive decline Anxiety NMS parkinsonism Postural instability Bradykinesia Depression Sleep disorder Dyskinesia Show more (+10) |
Anxiety
Depression |
|
No
|
♀
|
n.a.
|
PHL
|
27
|
50
|
Yes
|
Tremor (any or unspecified)
Tremor at rest -Motor Dyskinesia Postural instability Bradykinesia Motor fluctuations Parkinsonism Show more (+5) |
n.a.
|
|
Yes
|
♀
|
n.a.
|
TWN
|
18
|
40
|
Yes
|
Parkinsonism
Dystonia Motor fluctuations Dyskinesia Tremor (any or unspecified) Sleep benefit Tremor at rest -Motor Bradykinesia Rigidity Show more (+7) |
n.a.
|
|
Yes
|
♂
|
A
|
JPN
|
30
|
47
|
Yes
|
Postural instability
Hyperreflexia -Motor Dyskinesia Bradykinesia Parkinsonism Rigidity Motor fluctuations Show more (+5) |
n.a.
|
|
Yes
|
♀
|
A
|
JPN
|
23
|
38
|
No
|
Motor fluctuations
Tremor at rest Sleep benefit Postural instability Rigidity Psychotic sign/sympt. Parkinsonism NMS parkinsonism Tremor (any or unspecified) -Motor Bradykinesia Hyperreflexia Show more (+9) |
n.a.
|
|
No
|
♀
|
n.a.
|
PHL
|
32
|
51
|
Yes
|
Postural instability
-Motor Motor fluctuations Rigidity Tremor at rest Bradykinesia Parkinsonism Tremor (any or unspecified) Show more (+5) |
n.a.
|
|
Yes
|
♀
|
n.a.
|
PHL
|
27
|
45
|
Yes
|
-Motor
Bradykinesia Rigidity Tremor (any or unspecified) Postural instability Motor fluctuations Tremor at rest Dyskinesia Parkinsonism Show more (+6) |
n.a.
|
|
Yes
|
♂
|
O
|
ISR
|
25
|
47
|
Yes
|
Cognitive decline
Dyskinesia NMS parkinsonism Anxiety Parkinsonism -Motor Motor fluctuations Sleep benefit Postural instability Hyperreflexia Psychotic sign/sympt. Bradykinesia Depression Rigidity Show more (+11) |
Anxiety
Depression |