Hatano, 2004: Overview of all reported PARK-PINK1 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♀
|
A
|
JPN
|
33
|
41
|
No
|
Bradykinesia
Parkinsonism Dystonia Motor fluctuations Dyskinesia NMS parkinsonism Postural instability Postural tremor Hyperreflexia -Motor Tremor (any or unspecified) Rigidity Psychotic sign/sympt. Show more (+10) |
n.a.
|
|
No
|
♀
|
n.a.
|
TWN
|
19
|
43
|
Yes
|
Sleep benefit
-Motor Tremor (any or unspecified) Dyskinesia Motor fluctuations Parkinsonism Rigidity Bradykinesia Tremor at rest Show more (+6) |
n.a.
|
|
No
|
♂
|
O
|
ISR
|
33
|
52
|
Yes
|
Parkinsonism
Bradykinesia Cognitive decline NMS parkinsonism Psychotic sign/sympt. Anxiety -Motor Depression Postural instability Motor fluctuations Sleep disorder Dyskinesia Rigidity Show more (+10) |
Anxiety
Depression |
|
No
|
♀
|
n.a.
|
PHL
|
27
|
50
|
Yes
|
Tremor at rest
-Motor Motor fluctuations Postural instability Parkinsonism Tremor (any or unspecified) Bradykinesia Dyskinesia Show more (+5) |
n.a.
|
|
Yes
|
♀
|
n.a.
|
TWN
|
18
|
40
|
Yes
|
Bradykinesia
Rigidity Tremor (any or unspecified) Tremor at rest Dyskinesia Motor fluctuations -Motor Parkinsonism Sleep benefit Dystonia Show more (+7) |
n.a.
|
|
Yes
|
♂
|
A
|
JPN
|
30
|
47
|
Yes
|
Dyskinesia
Postural instability -Motor Bradykinesia Motor fluctuations Rigidity Parkinsonism Hyperreflexia Show more (+5) |
n.a.
|
|
Yes
|
♀
|
A
|
JPN
|
23
|
38
|
No
|
Motor fluctuations
NMS parkinsonism Postural instability Psychotic sign/sympt. Parkinsonism Hyperreflexia Tremor (any or unspecified) Tremor at rest Bradykinesia -Motor Sleep benefit Rigidity Show more (+9) |
n.a.
|
|
No
|
♀
|
n.a.
|
PHL
|
32
|
51
|
Yes
|
Postural instability
-Motor Bradykinesia Rigidity Tremor at rest Parkinsonism Tremor (any or unspecified) Motor fluctuations Show more (+5) |
n.a.
|
|
Yes
|
♀
|
n.a.
|
PHL
|
27
|
45
|
Yes
|
Tremor at rest
Motor fluctuations Dyskinesia Bradykinesia Parkinsonism Rigidity Tremor (any or unspecified) -Motor Postural instability Show more (+6) |
n.a.
|
|
Yes
|
♂
|
O
|
ISR
|
25
|
47
|
Yes
|
Parkinsonism
Psychotic sign/sympt. Bradykinesia Motor fluctuations Anxiety Hyperreflexia NMS parkinsonism Depression Cognitive decline Dyskinesia Sleep benefit Rigidity -Motor Postural instability Show more (+11) |
Anxiety
Depression |