Hatano, 2004: Overview of all reported PARK-PINK1 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♀
|
A
|
JPN
|
33
|
41
|
No
|
Postural instability
Postural tremor Dystonia -Motor Dyskinesia Motor fluctuations Rigidity NMS parkinsonism Psychotic sign/sympt. Bradykinesia Tremor (any or unspecified) Parkinsonism Hyperreflexia Show more (+10) |
n.a.
|
|
No
|
♀
|
n.a.
|
TWN
|
19
|
43
|
Yes
|
-Motor
Parkinsonism Sleep benefit Tremor at rest Dyskinesia Tremor (any or unspecified) Bradykinesia Motor fluctuations Rigidity Show more (+6) |
n.a.
|
|
No
|
♂
|
O
|
ISR
|
33
|
52
|
Yes
|
Cognitive decline
Motor fluctuations -Motor Rigidity Depression Dyskinesia Psychotic sign/sympt. NMS parkinsonism Postural instability Bradykinesia Parkinsonism Anxiety Sleep disorder Show more (+10) |
Depression
Anxiety |
|
No
|
♀
|
n.a.
|
PHL
|
27
|
50
|
Yes
|
-Motor
Tremor (any or unspecified) Tremor at rest Motor fluctuations Bradykinesia Dyskinesia Postural instability Parkinsonism Show more (+5) |
n.a.
|
|
Yes
|
♀
|
n.a.
|
TWN
|
18
|
40
|
Yes
|
Motor fluctuations
Rigidity Sleep benefit Tremor (any or unspecified) Parkinsonism Tremor at rest Dystonia -Motor Bradykinesia Dyskinesia Show more (+7) |
n.a.
|
|
Yes
|
♂
|
A
|
JPN
|
30
|
47
|
Yes
|
Bradykinesia
Hyperreflexia Dyskinesia Parkinsonism Motor fluctuations Postural instability -Motor Rigidity Show more (+5) |
n.a.
|
|
Yes
|
♀
|
A
|
JPN
|
23
|
38
|
No
|
Motor fluctuations
Sleep benefit -Motor Rigidity Bradykinesia Tremor at rest Hyperreflexia Postural instability Psychotic sign/sympt. NMS parkinsonism Parkinsonism Tremor (any or unspecified) Show more (+9) |
n.a.
|
|
No
|
♀
|
n.a.
|
PHL
|
32
|
51
|
Yes
|
Tremor (any or unspecified)
Bradykinesia Tremor at rest Parkinsonism Rigidity Postural instability -Motor Motor fluctuations Show more (+5) |
n.a.
|
|
Yes
|
♀
|
n.a.
|
PHL
|
27
|
45
|
Yes
|
Dyskinesia
Motor fluctuations Rigidity Parkinsonism Bradykinesia Postural instability Tremor at rest Tremor (any or unspecified) -Motor Show more (+6) |
n.a.
|
|
Yes
|
♂
|
O
|
ISR
|
25
|
47
|
Yes
|
-Motor
NMS parkinsonism Parkinsonism Rigidity Psychotic sign/sympt. Bradykinesia Dyskinesia Sleep benefit Cognitive decline Hyperreflexia Depression Motor fluctuations Postural instability Anxiety Show more (+11) |
Depression
Anxiety |