Hatano, 2004: Overview of all reported PARK-PINK1 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♀
|
A
|
JPN
|
33
|
41
|
No
|
Postural instability
Bradykinesia -Motor Motor fluctuations Psychotic sign/sympt. Tremor (any or unspecified) Postural tremor Dyskinesia Rigidity Dystonia NMS parkinsonism Parkinsonism Hyperreflexia Show more (+10) |
n.a.
|
|
No
|
♀
|
n.a.
|
TWN
|
19
|
43
|
Yes
|
Motor fluctuations
Bradykinesia Tremor at rest Sleep benefit Tremor (any or unspecified) -Motor Parkinsonism Rigidity Dyskinesia Show more (+6) |
n.a.
|
|
No
|
♂
|
O
|
ISR
|
33
|
52
|
Yes
|
Motor fluctuations
Dyskinesia Postural instability NMS parkinsonism Bradykinesia Anxiety Depression Sleep disorder Parkinsonism -Motor Cognitive decline Rigidity Psychotic sign/sympt. Show more (+10) |
Anxiety
Depression |
|
No
|
♀
|
n.a.
|
PHL
|
27
|
50
|
Yes
|
Dyskinesia
Postural instability Bradykinesia Tremor at rest Parkinsonism Tremor (any or unspecified) Motor fluctuations -Motor Show more (+5) |
n.a.
|
|
Yes
|
♀
|
n.a.
|
TWN
|
18
|
40
|
Yes
|
Dyskinesia
-Motor Dystonia Tremor (any or unspecified) Rigidity Tremor at rest Motor fluctuations Sleep benefit Bradykinesia Parkinsonism Show more (+7) |
n.a.
|
|
Yes
|
♂
|
A
|
JPN
|
30
|
47
|
Yes
|
Parkinsonism
-Motor Motor fluctuations Dyskinesia Bradykinesia Rigidity Hyperreflexia Postural instability Show more (+5) |
n.a.
|
|
Yes
|
♀
|
A
|
JPN
|
23
|
38
|
No
|
Postural instability
Rigidity Tremor at rest -Motor Bradykinesia Parkinsonism Psychotic sign/sympt. Tremor (any or unspecified) Hyperreflexia NMS parkinsonism Motor fluctuations Sleep benefit Show more (+9) |
n.a.
|
|
No
|
♀
|
n.a.
|
PHL
|
32
|
51
|
Yes
|
Rigidity
Postural instability Tremor (any or unspecified) Parkinsonism Tremor at rest -Motor Bradykinesia Motor fluctuations Show more (+5) |
n.a.
|
|
Yes
|
♀
|
n.a.
|
PHL
|
27
|
45
|
Yes
|
Motor fluctuations
Bradykinesia Parkinsonism -Motor Postural instability Rigidity Tremor at rest Dyskinesia Tremor (any or unspecified) Show more (+6) |
n.a.
|
|
Yes
|
♂
|
O
|
ISR
|
25
|
47
|
Yes
|
Sleep benefit
Parkinsonism Depression Rigidity Motor fluctuations Hyperreflexia Anxiety Dyskinesia Postural instability Psychotic sign/sympt. -Motor Bradykinesia NMS parkinsonism Cognitive decline Show more (+11) |
Depression
Anxiety |