Hatano, 2004: Overview of all reported PARK-PINK1 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♀
|
A
|
JPN
|
33
|
41
|
No
|
Motor fluctuations
Bradykinesia Tremor (any or unspecified) Rigidity NMS parkinsonism Postural instability -Motor Parkinsonism Dystonia Hyperreflexia Dyskinesia Postural tremor Psychotic sign/sympt. Show more (+10) |
n.a.
|
|
No
|
♀
|
n.a.
|
TWN
|
19
|
43
|
Yes
|
Sleep benefit
Tremor (any or unspecified) Parkinsonism -Motor Dyskinesia Rigidity Motor fluctuations Tremor at rest Bradykinesia Show more (+6) |
n.a.
|
|
No
|
♂
|
O
|
ISR
|
33
|
52
|
Yes
|
NMS parkinsonism
Psychotic sign/sympt. -Motor Dyskinesia Cognitive decline Parkinsonism Rigidity Anxiety Depression Motor fluctuations Postural instability Bradykinesia Sleep disorder Show more (+10) |
Anxiety
Depression |
|
No
|
♀
|
n.a.
|
PHL
|
27
|
50
|
Yes
|
Parkinsonism
Motor fluctuations Dyskinesia Tremor at rest -Motor Tremor (any or unspecified) Bradykinesia Postural instability Show more (+5) |
n.a.
|
|
Yes
|
♀
|
n.a.
|
TWN
|
18
|
40
|
Yes
|
-Motor
Bradykinesia Rigidity Tremor (any or unspecified) Dystonia Sleep benefit Parkinsonism Motor fluctuations Tremor at rest Dyskinesia Show more (+7) |
n.a.
|
|
Yes
|
♂
|
A
|
JPN
|
30
|
47
|
Yes
|
Dyskinesia
Bradykinesia Hyperreflexia Parkinsonism Rigidity Motor fluctuations Postural instability -Motor Show more (+5) |
n.a.
|
|
Yes
|
♀
|
A
|
JPN
|
23
|
38
|
No
|
Rigidity
Postural instability Psychotic sign/sympt. Bradykinesia Tremor at rest Tremor (any or unspecified) Parkinsonism NMS parkinsonism Hyperreflexia -Motor Motor fluctuations Sleep benefit Show more (+9) |
n.a.
|
|
No
|
♀
|
n.a.
|
PHL
|
32
|
51
|
Yes
|
-Motor
Parkinsonism Bradykinesia Tremor (any or unspecified) Tremor at rest Postural instability Rigidity Motor fluctuations Show more (+5) |
n.a.
|
|
Yes
|
♀
|
n.a.
|
PHL
|
27
|
45
|
Yes
|
-Motor
Dyskinesia Bradykinesia Postural instability Rigidity Tremor at rest Tremor (any or unspecified) Parkinsonism Motor fluctuations Show more (+6) |
n.a.
|
|
Yes
|
♂
|
O
|
ISR
|
25
|
47
|
Yes
|
Dyskinesia
Rigidity Motor fluctuations Psychotic sign/sympt. -Motor Anxiety Hyperreflexia Bradykinesia Sleep benefit Depression Parkinsonism Cognitive decline Postural instability NMS parkinsonism Show more (+11) |
Anxiety
Depression |