Farrer, 2009: Overview of all reported PARK-DCTN1 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♂
|
n.a.
|
USA
|
41
|
42
|
n.a.
|
Hypomimia
Postural instability Hypoventilation respiratory complications Atypical parkinsonism Respiratory sighs Apathy fatigue Parkinsonism Bradykinesia Decreased body weight Sleep disorder Rigidity Tremor (any or unspecified) Behavioral abnormalities Show more (+10) |
Apathy fatigue
Sleep disorder Tremor (any or unspecified) |
|
No
|
♂
|
n.a.
|
CAN
|
52
|
n.a.
|
n.a.
|
Parkinsonism
Decreased body weight Atypical parkinsonism Respiratory sighs Bradykinesia Hypoventilation respiratory complications Show more (+3) |
n.a.
|
|
Yes
|
♀
|
n.a.
|
FRA
|
56
|
n.a.
|
n.a.
|
Hypoventilation respiratory complications
Bradykinesia Parkinsonism Decreased body weight Respiratory sighs Show more (+2) |
n.a.
|
|
No
|
♀
|
n.a.
|
JPN
|
47
|
n.a.
|
n.a.
|
Parkinsonism
Respiratory sighs Bradykinesia |
n.a.
|
|
Yes
|
♂
|
n.a.
|
TUR
|
46
|
50
|
n.a.
|
Respiratory sighs
Tremor at rest Hypoventilation respiratory complications Parkinsonism Tremor (any or unspecified) Dysarthria Decreased body weight Atypical parkinsonism Apathy fatigue Depression Bradykinesia Show more (+8) |
Apathy fatigue
Depression |
|
No
|
♀
|
n.a.
|
FRA
|
48
|
n.a.
|
n.a.
|
Bradykinesia
Parkinsonism Decreased body weight Respiratory sighs Hypoventilation respiratory complications Show more (+2) |
n.a.
|
|
No
|
♀
|
n.a.
|
TUR
|
51
|
53
|
n.a.
|
Postural instability
Apathy fatigue Sleep disorder Hypoventilation respiratory complications Behavioral abnormalities Impulsive control disorder Cognitive decline Bradykinesia Respiratory sighs Parkinsonism Decreased body weight Primitive reflexes Atypical parkinsonism Psychotic sign/sympt. Hypomimia Rigidity Show more (+13) |
Apathy fatigue
Sleep disorder Bradykinesia |
|
Yes
|
n.a.
|
n.a.
|
n.a.
|
49
|
n.a.
|
No
|
Decreased body weight
Parkinsonism Respiratory sighs Bradykinesia Hypoventilation respiratory complications Show more (+2) |
n.a.
|
|
No
|
n.a.
|
n.a.
|
CAN
|
54
|
56
|
n.a.
|
Parkinsonism
Depression Decreased body weight Respiratory sighs Anxiety Tremor at rest Atypical parkinsonism Hypoventilation respiratory complications Asymmetric onset Rigidity Bradykinesia Tremor (any or unspecified) Show more (+9) |
Depression
Anxiety |
|
No
|
♂
|
n.a.
|
JPN
|
38
|
n.a.
|
n.a.
|
Respiratory sighs
Bradykinesia Decreased body weight Parkinsonism Hypoventilation respiratory complications Show more (+2) |
n.a.
|