Marongiu, 2006: Overview of all reported PARK-LRRK2 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♂
|
n.a.
|
ITA
|
63
|
71
|
Yes
|
Depression
Bradykinesia Parkinsonism Rigidity Anxiety Motor fluctuations NMS parkinsonism -Motor Show more (+5) |
Bradykinesia
|
|
Yes
|
♀
|
n.a.
|
ITA
|
42
|
52
|
No
|
Rigidity
Dyskinesia Depression NMS parkinsonism Parkinsonism -Motor Motor fluctuations Bradykinesia Show more (+5) |
Bradykinesia
|
|
Yes
|
♀
|
n.a.
|
ITA
|
46
|
54
|
Yes
|
-Motor
Parkinsonism Rigidity Tremor (any or unspecified) Tremor at rest Bradykinesia Hyperreflexia Show more (+4) |
Tremor (any or unspecified)
|
|
Yes
|
♀
|
n.a.
|
ITA
|
71
|
84
|
Yes
|
Depression
Cognitive decline Anxiety Hyperreflexia Tremor (any or unspecified) Bradykinesia Tremor at rest -Motor Parkinsonism NMS parkinsonism Show more (+7) |
Tremor (any or unspecified)
|
|
Yes
|
♀
|
n.a.
|
ITA
|
61
|
73
|
No
|
Depression
Bradykinesia Tremor at rest Dyskinesia NMS parkinsonism Tremor (any or unspecified) Motor fluctuations -Motor Parkinsonism Rigidity Show more (+7) |
Tremor (any or unspecified)
|
|
Yes
|
♂
|
n.a.
|
ITA
|
71
|
81
|
Yes
|
Rigidity
|
||
Yes
|
♂
|
n.a.
|
ITA
|
70
|
75
|
No
|
-Motor
Tremor at rest Parkinsonism Rigidity Tremor (any or unspecified) Bradykinesia Depression NMS parkinsonism Show more (+5) |
Tremor (any or unspecified)
|
|
Yes
|
♀
|
n.a.
|
ITA
|
59
|
65
|
Yes
|
Motor fluctuations
Tremor (any or unspecified) Parkinsonism Bradykinesia Tremor at rest -Motor Rigidity Show more (+4) |
Bradykinesia
|
|
Yes
|
♀
|
n.a.
|
ITA
|
44
|
57
|
No
|
Parkinsonism
Rigidity Bradykinesia Dyskinesia NMS parkinsonism -Motor Motor fluctuations Anxiety Autonomic sign/sympt. Depression Show more (+7) |
Bradykinesia
|
|
Yes
|
♀
|
n.a.
|
ITA
|
52
|
60
|
No
|
Rigidity
Parkinsonism Tremor (any or unspecified) -Motor Tremor at rest Bradykinesia Hyperreflexia Dyskinesia NMS parkinsonism Anxiety Show more (+7) |
Bradykinesia
|