Marongiu, 2006: Overview of all reported PARK-LRRK2 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♂
|
n.a.
|
ITA
|
63
|
71
|
Yes
|
Depression
Anxiety NMS parkinsonism -Motor Motor fluctuations Bradykinesia Rigidity Parkinsonism Show more (+5) |
Bradykinesia
|
|
Yes
|
♀
|
n.a.
|
ITA
|
42
|
52
|
No
|
Depression
Parkinsonism NMS parkinsonism Bradykinesia Rigidity -Motor Dyskinesia Motor fluctuations Show more (+5) |
Bradykinesia
|
|
Yes
|
♀
|
n.a.
|
ITA
|
46
|
54
|
Yes
|
Hyperreflexia
Parkinsonism Tremor (any or unspecified) Rigidity -Motor Bradykinesia Tremor at rest Show more (+4) |
Tremor (any or unspecified)
|
|
Yes
|
♀
|
n.a.
|
ITA
|
71
|
84
|
Yes
|
Tremor (any or unspecified)
Depression Hyperreflexia NMS parkinsonism Parkinsonism -Motor Cognitive decline Anxiety Tremor at rest Bradykinesia Show more (+7) |
Tremor (any or unspecified)
|
|
Yes
|
♀
|
n.a.
|
ITA
|
61
|
73
|
No
|
Depression
Motor fluctuations Rigidity NMS parkinsonism Bradykinesia -Motor Tremor at rest Parkinsonism Dyskinesia Tremor (any or unspecified) Show more (+7) |
Tremor (any or unspecified)
|
|
Yes
|
♂
|
n.a.
|
ITA
|
71
|
81
|
Yes
|
Rigidity
|
||
Yes
|
♂
|
n.a.
|
ITA
|
70
|
75
|
No
|
-Motor
Depression Tremor (any or unspecified) Parkinsonism NMS parkinsonism Tremor at rest Bradykinesia Rigidity Show more (+5) |
Tremor (any or unspecified)
|
|
Yes
|
♀
|
n.a.
|
ITA
|
59
|
65
|
Yes
|
Tremor at rest
Parkinsonism Motor fluctuations Tremor (any or unspecified) Rigidity Bradykinesia -Motor Show more (+4) |
Bradykinesia
|
|
Yes
|
♀
|
n.a.
|
ITA
|
44
|
57
|
No
|
Parkinsonism
Bradykinesia Motor fluctuations Autonomic sign/sympt. Dyskinesia Anxiety NMS parkinsonism Rigidity Depression -Motor Show more (+7) |
Bradykinesia
|
|
Yes
|
♀
|
n.a.
|
ITA
|
52
|
60
|
No
|
Bradykinesia
-Motor Hyperreflexia Parkinsonism Tremor (any or unspecified) NMS parkinsonism Rigidity Dyskinesia Anxiety Tremor at rest Show more (+7) |
Bradykinesia
|