Marongiu, 2006: Overview of all reported PARK-LRRK2 patients

Index patient Sex Ethnicity Country of origin AAO AAE Family history Symptoms Initial symptoms Reported mutations
Yes
n.a.
ITA
63
71
Yes
Rigidity
NMS parkinsonism
Parkinsonism
Motor fluctuations
Depression
Anxiety
Bradykinesia
-Motor
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Bradykinesia
Gly2019Ser: het
Yes
n.a.
ITA
42
52
No
-Motor
Dyskinesia
Depression
Parkinsonism
Rigidity
Bradykinesia
Motor fluctuations
NMS parkinsonism
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Bradykinesia
Gly2019Ser: het
Yes
n.a.
ITA
46
54
Yes
Hyperreflexia
Tremor (any or unspecified)
-Motor
Rigidity
Parkinsonism
Tremor at rest
Bradykinesia
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Tremor (any or unspecified)
Gly2019Ser: het
Yes
n.a.
ITA
71
84
Yes
Hyperreflexia
-Motor
Depression
NMS parkinsonism
Tremor at rest
Parkinsonism
Cognitive decline
Anxiety
Tremor (any or unspecified)
Bradykinesia
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Tremor (any or unspecified)
Gly2019Ser: het
Yes
n.a.
ITA
61
73
No
Depression
Rigidity
Tremor (any or unspecified)
Bradykinesia
Parkinsonism
NMS parkinsonism
-Motor
Motor fluctuations
Dyskinesia
Tremor at rest
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Tremor (any or unspecified)
Gly2019Ser: het
Yes
n.a.
ITA
71
81
Yes
Bradykinesia
Tremor (any or unspecified)
Rigidity
Tremor at rest
-Motor
Parkinsonism
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Rigidity
Gly2019Ser: het
Yes
n.a.
ITA
70
75
No
-Motor
Rigidity
Tremor (any or unspecified)
Bradykinesia
Tremor at rest
Depression
Parkinsonism
NMS parkinsonism
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Tremor (any or unspecified)
Gly2019Ser: het
Yes
n.a.
ITA
59
65
Yes
-Motor
Rigidity
Motor fluctuations
Parkinsonism
Bradykinesia
Tremor at rest
Tremor (any or unspecified)
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Bradykinesia
Gly2019Ser: het
Yes
n.a.
ITA
44
57
No
Autonomic sign/sympt.
Bradykinesia
NMS parkinsonism
Depression
Parkinsonism
Dyskinesia
-Motor
Anxiety
Motor fluctuations
Rigidity
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Bradykinesia
Gly2019Ser: het
Yes
n.a.
ITA
52
60
No
-Motor
Parkinsonism
Tremor at rest
Rigidity
Hyperreflexia
Tremor (any or unspecified)
Dyskinesia
NMS parkinsonism
Bradykinesia
Anxiety
Show more (+7)
Bradykinesia
Gly2019Ser: het