Marongiu, 2006: Overview of all reported PARK-LRRK2 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♂
|
n.a.
|
ITA
|
40
|
41
|
No
|
-Motor
NMS parkinsonism Tremor (any or unspecified) Parkinsonism Rigidity Tremor at rest Anxiety Bradykinesia Show more (+5) |
Rigidity
|
|
Yes
|
♀
|
n.a.
|
ITA
|
78
|
81
|
Yes
|
Tremor at rest
Cognitive decline Dyskinesia Tremor (any or unspecified) Parkinsonism -Motor Rigidity Bradykinesia Show more (+5) |
Tremor (any or unspecified)
|
|
Yes
|
♂
|
n.a.
|
ITA
|
58
|
69
|
No
|
Rigidity
|
||
Yes
|
♀
|
n.a.
|
ITA
|
55
|
75
|
Yes
|
Bradykinesia
NMS parkinsonism Parkinsonism Rigidity -Motor Motor fluctuations Dyskinesia Show more (+4) |
Rigidity
|
|
Yes
|
♂
|
n.a.
|
ITA
|
58
|
78
|
No
|
Rigidity
Dyskinesia Parkinsonism Bradykinesia Motor fluctuations Tremor (any or unspecified) Tremor at rest -Motor Show more (+5) |
Tremor (any or unspecified)
|
|
Yes
|
♀
|
n.a.
|
ITA
|
57
|
65
|
Yes
|
Tremor (any or unspecified)
Autonomic sign/sympt. Parkinsonism Rigidity Dyskinesia Motor fluctuations Tremor at rest Bradykinesia NMS parkinsonism -Motor Show more (+7) |
Rigidity
|
|
Yes
|
♀
|
n.a.
|
ITA
|
54
|
60
|
Yes
|
Parkinsonism
Autonomic sign/sympt. -Motor NMS parkinsonism Tremor at rest Depression Tremor (any or unspecified) Rigidity Show more (+5) |
Tremor (any or unspecified)
|
|
Yes
|
♂
|
n.a.
|
ITA
|
35
|
40
|
No
|
Bradykinesia
|
||
Yes
|
♂
|
n.a.
|
ITA
|
39
|
44
|
No
|
Tremor (any or unspecified)
Bradykinesia NMS parkinsonism Tremor at rest Parkinsonism -Motor Hyperreflexia Anxiety Rigidity Dyskinesia Show more (+7) |
Tremor (any or unspecified)
|
|
Yes
|
♀
|
n.a.
|
ITA
|
47
|
60
|
No
|
Depression
Rigidity Parkinsonism -Motor Bradykinesia Tremor at rest Tremor (any or unspecified) NMS parkinsonism Show more (+5) |
Tremor (any or unspecified)
|