Lu, 2018: Overview of all reported HSP-SPAST patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♂
|
A
|
CHN
|
60
|
64
|
n.a.
|
Babinski sign
-Pure or uncomplicated |
n.a.
|
|
Yes
|
♂
|
A
|
CHN
|
32
|
45
|
n.a.
|
Babinski sign
|
n.a.
|
|
Yes
|
♀
|
A
|
CHN
|
51
|
52
|
n.a.
|
Nystagmus
Dysarthria |
n.a.
|
|
Yes
|
♀
|
A
|
CHN
|
61
|
71
|
n.a.
|
-Pure or uncomplicated
Babinski sign Lower limb muscle weakness |
n.a.
|
|
Yes
|
♂
|
A
|
CHN
|
35
|
42
|
n.a.
|
-Pure or uncomplicated
Hyperreflexia in upper limbs Babinski sign |
n.a.
|
|
Yes
|
♂
|
A
|
CHN
|
43
|
53
|
n.a.
|
Nystagmus
Hyperreflexia in upper limbs Babinski sign |
n.a.
|
|
Yes
|
♂
|
A
|
CHN
|
25
|
45
|
n.a.
|
-Pure or uncomplicated
Hyperreflexia in upper limbs Babinski sign |
n.a.
|
|
Yes
|
♂
|
A
|
CHN
|
37
|
38
|
n.a.
|
Lower limb muscle weakness
Hyperreflexia in upper limbs Babinski sign |
n.a.
|
|
Yes
|
♂
|
A
|
CHN
|
16
|
26
|
n.a.
|
Nystagmus
Hyperreflexia in upper limbs Babinski sign |
n.a.
|
|
Yes
|
♀
|
A
|
CHN
|
50
|
55
|
n.a.
|
Babinski sign
|
n.a.
|
|
Yes
|
♀
|
A
|
CHN
|
40
|
45
|
n.a.
|
n.a.
|
||
Yes
|
♀
|
A
|
CHN
|
24
|
37
|
n.a.
|
Hyperreflexia in upper limbs
Babinski sign -Pure or uncomplicated |
n.a.
|
|
Yes
|
♂
|
A
|
CHN
|
46
|
52
|
n.a.
|
Hyperreflexia in upper limbs
-Pure or uncomplicated Babinski sign |
n.a.
|
|
Yes
|
♀
|
A
|
CHN
|
40
|
55
|
n.a.
|
n.a.
|
||
Yes
|
♀
|
A
|
CHN
|
7
|
11
|
n.a.
|
n.a.
|
||
Yes
|
♂
|
A
|
CHN
|
35
|
49
|
n.a.
|
n.a.
|
||
Yes
|
♂
|
A
|
CHN
|
43
|
44
|
n.a.
|
-Pure or uncomplicated
Babinski sign |
n.a.
|
|
Yes
|
♂
|
A
|
CHN
|
10
|
47
|
n.a.
|
Hyperreflexia in upper limbs
-Pure or uncomplicated Babinski sign |
n.a.
|
|
Yes
|
♂
|
A
|
CHN
|
34
|
35
|
n.a.
|
-Pure or uncomplicated
Nystagmus Hyperreflexia in upper limbs |
n.a.
|
|
Yes
|
♂
|
A
|
CHN
|
4
|
14
|
n.a.
|
-Pure or uncomplicated
Babinski sign |
n.a.
|
|
Yes
|
♂
|
A
|
CHN
|
43
|
51
|
n.a.
|
n.a.
|
||
Yes
|
♀
|
A
|
CHN
|
36
|
43
|
n.a.
|
Lower limb muscle weakness
-Pure or uncomplicated Babinski sign Hyperreflexia in upper limbs Show more (+1) |
n.a.
|