No

♂

C

BRA

n.a.

n.a.

Yes

Parkinsonism
-Motor
Bradykinesia

n.a.

p.Pro397Alafs*18: het

Yes

♂

C

FRA

51

n.a.

No

Bradykinesia
Rigidity
-Motor
Dystonia
Parkinsonism
Brain calcification
Dyskinesia
Show more (+4)

n.a.

p.Tyr386*: het

Yes

♀

C

FRA

72

n.a.

No

-Motor
Speech disturbance
Bradykinesia
Tremor (any or unspecified)
Parkinsonism
Rigidity
Brain calcification
Show more (+4)

n.a.

c.289+5G>A: het

Yes

♀

C

FRA

71

n.a.

No

Cognitive decline
Parkinsonism
-Motor
Cerebellar signs
Bradykinesia
Brain calcification
Rigidity
Show more (+4)

n.a.

c.1524-2A>G: het

Yes

♂

C

ITA

68

n.a.

Yes

Cerebellar signs
Parkinsonism
Speech disturbance
Brain calcification
Rigidity
Bradykinesia
-Motor
Show more (+4)

n.a.

p.Gly498Arg: het

Yes

♀

C

FRA

33

n.a.

Yes

Dystonia
Brain calcification
Tremor, action
-Motor
Migraine (any subclass)
Tremor (any or unspecified)
Cerebellar signs
Bradykinesia
Headache
Parkinsonism
Psychotic sign/sympt.
Show more (+8)

n.a.

p.Ser508Asn: het

Yes

♀

C

FRA

40

n.a.

No

Parkinsonism
Brain calcification
Bradykinesia
Tremor (any or unspecified)
Cognitive decline
-Motor
Show more (+3)

n.a.

c.730+1G>T: het

Yes

♀

C

BRA

n.a.

n.a.

Yes

-Motor
Speech disturbance
Bradykinesia
Parkinsonism
Show more (+1)

n.a.

p.Pro397Alafs*18: het

Yes

♂

C

USA

60

n.a.

Yes

Brain calcification
Chorea
Headache
-Motor
Show more (+1)

n.a.

p.Arg181Trp: het

Yes

♂

C

USA

n.a.

n.a.

No

-Motor
Brain calcification
Parkinsonism
Bradykinesia
Rigidity
Show more (+2)

n.a.

p.Gly498Arg: het

Yes

♂

C

FRA

65

n.a.

No

Rigidity
Bradykinesia
-Motor
Brain calcification
Parkinsonism
Show more (+2)

n.a.

p.Arg403*: het

Yes

♂

C

FRA

3

n.a.

Yes

-Motor
Tremor, action
Rigidity
Tremor (any or unspecified)
Cognitive decline
Psychotic sign/sympt.
Ataxia
Cerebellar signs
Parkinsonism
Brain calcification
Postural tremor
Bradykinesia
Show more (+9)

n.a.

p.Asn587Serfs*7: het

Yes

♂

C

FRA

68

n.a.

Yes

Cerebellar signs
Tremor (any or unspecified)
Parkinsonism
Rigidity
Ataxia
Cognitive decline
-Motor
Brain calcification
Bradykinesia
Show more (+6)

n.a.

p.Asn194Ser: het

Yes

♀

C

ITA

3

n.a.

No

Postural tremor
Brain calcification
Tremor, action
Tremor (any or unspecified)
-Motor
Parkinsonism
Bradykinesia
Show more (+4)

n.a.

p.Ser434Trp: het

Yes

♂

C

FRA

44

n.a.

Yes

Rigidity
-Motor
Ataxia
Psychotic sign/sympt.
Parkinsonism
Brain calcification
Bradykinesia
Cerebellar signs
Show more (+5)

n.a.

p.Glu476*: het

No

♂

C

USA

n.a.

n.a.

Yes

Anxiety
Brain calcification
Parkinsonism
-Motor
Dystonia
Show more (+2)

n.a.

p.Ile608_Trp616del: het

Yes

♂

C

FRA

7

n.a.

No

-Motor
Parkinsonism
Brain calcification
Cognitive decline
Tremor (any or unspecified)
Show more (+2)

n.a.

p.Val624Glu: het

Yes

♀

C

FRA

63

n.a.

No

-Motor
Brain calcification
Psychotic sign/sympt.

n.a.

p.Leu50*: het

Yes

♀

C

FRA

n.a.

n.a.

No

Parkinsonism
Cognitive decline
-Motor
Bradykinesia
Brain calcification
Show more (+2)

n.a.

p.Ala585Thr: het

Yes

♂

C

FRA

76

n.a.

No

Ataxia
Cerebellar signs
Speech disturbance
Brain calcification
-Motor
Depression
Show more (+3)

n.a.

p.Val128Serfs*43: het

Yes

♂

C

ITA

65

n.a.

Yes

Brain calcification
Dystonia
Cognitive decline
-Motor
Chorea
Show more (+2)

n.a.

p.Gln247*: het

No

♀

C

FRA

26

n.a.

Yes

-Motor
Brain calcification

n.a.

p.Pro184Leu: het