Paisan-Ruiz, 2009: Overview of all reported DYT/PARK-PLA2G6 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
♀
|
n.a.
|
IND
|
10
|
n.a.
|
n.a.
|
Tremor (any or unspecified)
Dyskinesia Bradykinesia Tremor, limb Parkinsonism Gait disturbance Abnormal central motor function Dystonia (any or unspecified) Rigidity Show more (+6) |
n.a.
|
|
Yes
|
♂
|
n.a.
|
PAK
|
18
|
21
|
n.a.
|
Abnormal central motor function
Dystonia, axial Cognitive impairment Psychiatric disorders Bradykinesia Myoclonus Dystonia, foot Datscan/trodat with evidence of dopaminergic deficit Pyramidal sign NMS parkinsonism Mri brain other abnormalities Spasticity Postural instability Autonomic sign/sympt. Hyperreflexia Dystonia (any or unspecified) Gait disturbance Rigidity Show more (+15) |
n.a.
|
|
Yes
|
♀
|
n.a.
|
IND
|
26
|
34
|
No
|
Dyskinesia
Dysarthria NMS parkinsonism Tremor (any or unspecified) Bradykinesia Datscan/trodat with evidence of dopaminergic deficit Pyramidal sign Hand tremor Abnormal central motor function Dystonia, arm Tremor, limb Dystonia (any or unspecified) Hyperreflexia Abnormal eye movement Hypomimic face Dystonia, limb Postural tremor Dystonia, leg Depression Parkinsonism Postural tremor, upper limb Rigidity Postural instability Cognitive impairment Resting tremor Mri brain other abnormalities Show more (+23) |
n.a.
|