Yoshino, 2010: Overview of all reported DYT/PARK-PLA2G6-(NBIA) patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♂
|
n.a.
|
JPN
|
25
|
34
|
n.a.
|
Parkinsonism
Dyskinesia Gait disturbance Cognitive impairment Bradykinesia Motor fluctuations Abnormal central motor function NMS parkinsonism Rigidity Autonomic sign/sympt. Mri brain other abnormalities Postural instability Show more (+9) |
Gait disturbance
|
|
Yes
|
♀
|
n.a.
|
JPN
|
20
|
35
|
n.a.
|
Autonomic sign/sympt.
Psychiatric disorders Sleep benefit Hypointensity on basal ganglia and or nigra Resting tremor Cognitive impairment Mri brain other abnormalities Tremor (any or unspecified) NMS parkinsonism Parkinsonism Rigidity Gait disturbance Depression Motor fluctuations Postural instability Bradykinesia Psychosis Abnormal central motor function Dyskinesia Show more (+16) |
n.a.
|
|
No
|
♂
|
n.a.
|
JPN
|
30
|
38
|
n.a.
|
Dyskinesia
Mri brain other abnormalities Motor fluctuations Postural instability Cognitive impairment Psychiatric disorders Gait disturbance Rigidity Bradykinesia Abnormal central motor function Parkinsonism Autonomic sign/sympt. NMS parkinsonism Show more (+10) |
Gait disturbance
|