Lee, 2006: Overview of all reported DYT/PARK-PTS patients

Index patient Sex Ethnicity Country of origin AAO AAE Family history Symptoms Initial symptoms Reported mutations
No
A
CHN
n.a.
2
n.a.
Seizures
Cognitive impairment
Bradykinesia
Delayed speech and language development
Global developmental delay
Intellectual developmental disorder
Muscular hypotonia
Abnormal central motor function
Developmental delay/intellectual disability
Spasticity
Gait difficulties
Show more (+8)
n.a.
p.Asn52Ser: hom
Yes
A
CHN
n.a.
10
No
Gait difficulties
Cognitive impairment
Spasticity
Global developmental delay
Abnormal central motor function
Microcephaly
Intellectual developmental disorder
Developmental delay/intellectual disability
Muscular hypotonia
Seizures
Delayed speech and language development
Bradykinesia
Autonomic sign/sympt.
Show more (+10)
n.a.
No
A
CHN
n.a.
5
n.a.
Autonomic sign/sympt.
Seizures
Global developmental delay
Bradykinesia
Gait difficulties
Developmental delay/intellectual disability
Intellectual developmental disorder
Spasticity
Cognitive impairment
Muscular hypotonia
Delayed speech and language development
Abnormal central motor function
Show more (+9)
n.a.
Yes
A
CHN
n.a.
21
No
Gait difficulties
Muscular hypotonia
Intellectual developmental disorder
Abnormal central motor function
Dystonia (any or unspecified)
Developmental delay/intellectual disability
Spasticity
Cognitive impairment
Show more (+5)
n.a.
Yes
A
CHN
n.a.
7
n.a.
Muscular hypotonia
Gait difficulties
Intellectual developmental disorder
Spasticity
Cognitive impairment
Developmental delay/intellectual disability
Abnormal central motor function
Dystonia (any or unspecified)
Show more (+5)
n.a.
Yes
A
CHN
n.a.
1
No
Bradykinesia
Cognitive impairment
Global developmental delay
Intellectual developmental disorder
Developmental delay/intellectual disability
Abnormal central motor function
Delayed speech and language development
Spasticity
Muscular hypotonia
Seizures
Gait difficulties
Show more (+8)
n.a.
p.Asn52Ser: hom
Yes
A
CHN
n.a.
8
n.a.
Global developmental delay
Intellectual developmental disorder
Muscular hypotonia
Bradykinesia
Abnormal central motor function
Delayed speech and language development
Gait difficulties
Autonomic sign/sympt.
Spasticity
Seizures
Developmental delay/intellectual disability
Cognitive impairment
Show more (+9)
n.a.
Yes
A
CHN
n.a.
2
No
Global developmental delay
Muscular hypotonia
Microcephaly
Abnormal central motor function
Seizures
Cognitive impairment
Spasticity
Gait difficulties
Bradykinesia
Delayed speech and language development
Intellectual developmental disorder
Developmental delay/intellectual disability
Show more (+9)
n.a.
Yes
A
CHN
n.a.
1
No
Spasticity
Abnormal central motor function
Microcephaly
Intellectual developmental disorder
Muscular hypotonia
Autonomic sign/sympt.
Seizures
Global developmental delay
Gait difficulties
Developmental delay/intellectual disability
Delayed speech and language development
Cognitive impairment
Bradykinesia
Show more (+10)
n.a.
Yes
A
CHN
n.a.
2
n.a.
Bradykinesia
Delayed speech and language development
Abnormal central motor function
Seizures
Global developmental delay
Spasticity
Microcephaly
Muscular hypotonia
Intellectual developmental disorder
Cognitive impairment
Gait difficulties
Developmental delay/intellectual disability
Show more (+9)
n.a.
p.Asn52Ser: hom