Mead, 2001: Overview of all reported HSP-SPAST patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
♀
|
n.a.
|
GBR
|
35
|
38
|
n.a.
|
Abnormality of the bladder
|
n.a.
|
|
No
|
♂
|
n.a.
|
GBR
|
35
|
40
|
n.a.
|
Impaired vibratory sensation
|
n.a.
|
|
No
|
♀
|
n.a.
|
GBR
|
35
|
57
|
n.a.
|
Impaired vibratory sensation
|
n.a.
|
|
No
|
♀
|
n.a.
|
GBR
|
60
|
82
|
n.a.
|
Abnormality of the bladder
Impaired vibratory sensation Walking aids |
n.a.
|
|
No
|
♀
|
n.a.
|
GBR
|
45
|
71
|
n.a.
|
Impaired vibratory sensation
Wheelchair Abnormality of the bladder Inability to walk Walking aids Show more (+2) |
n.a.
|
|
No
|
♂
|
n.a.
|
GBR
|
27
|
29
|
n.a.
|
n.a.
|
n.a.
|
|
No
|
♀
|
n.a.
|
GBR
|
24
|
32
|
n.a.
|
Abnormality of the bladder
Impaired vibratory sensation |
n.a.
|
|
No
|
♀
|
n.a.
|
GBR
|
25
|
50
|
n.a.
|
Abnormality of the bladder
Hyperreflexia in upper limbs Impaired proprioception Impaired vibratory sensation Spasticity, lower limb Mri brain other abnormalities Walking aids Impaired temperature sensation Abnormality of the cerebral white matter Impaired pain sensation Lower limb muscle weakness Show more (+8) |
n.a.
|
|
No
|
♀
|
n.a.
|
GBR
|
34
|
64
|
n.a.
|
Impaired vibratory sensation
Abnormality of the bladder Seizures |
n.a.
|
|
No
|
♀
|
n.a.
|
GBR
|
0
|
30
|
n.a.
|
Ataxia, limb
|
n.a.
|