Mead, 2001: Overview of all reported HSP-SPAST patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
♀
|
n.a.
|
GBR
|
35
|
38
|
n.a.
|
Abnormality of the bladder
|
n.a.
|
|
No
|
♂
|
n.a.
|
GBR
|
35
|
40
|
n.a.
|
Impaired vibratory sensation
|
n.a.
|
|
No
|
♀
|
n.a.
|
GBR
|
35
|
57
|
n.a.
|
Impaired vibratory sensation
|
n.a.
|
|
No
|
♀
|
n.a.
|
GBR
|
60
|
82
|
n.a.
|
Walking aids
Abnormality of the bladder Impaired vibratory sensation |
n.a.
|
|
No
|
♀
|
n.a.
|
GBR
|
45
|
71
|
n.a.
|
Abnormality of the bladder
Wheelchair Walking aids Inability to walk Impaired vibratory sensation Show more (+2) |
n.a.
|
|
No
|
♂
|
n.a.
|
GBR
|
27
|
29
|
n.a.
|
n.a.
|
n.a.
|
|
No
|
♀
|
n.a.
|
GBR
|
24
|
32
|
n.a.
|
Abnormality of the bladder
Impaired vibratory sensation |
n.a.
|
|
No
|
♀
|
n.a.
|
GBR
|
25
|
50
|
n.a.
|
Walking aids
Abnormality of the cerebral white matter Impaired vibratory sensation Abnormality of the bladder Impaired pain sensation Spasticity, lower limb Lower limb muscle weakness Mri brain other abnormalities Impaired temperature sensation Impaired proprioception Hyperreflexia in upper limbs Show more (+8) |
n.a.
|
|
No
|
♀
|
n.a.
|
GBR
|
34
|
64
|
n.a.
|
Seizures
Abnormality of the bladder Impaired vibratory sensation |
n.a.
|
|
No
|
♀
|
n.a.
|
GBR
|
0
|
30
|
n.a.
|
Ataxia, limb
|
n.a.
|