Vandebona, 2012: Overview of all reported HSP-SPAST patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
n.a.
|
O
|
AUS
|
25
|
n.a.
|
n.a.
|
Abnormality of the bladder
Hyperreflexia in upper limbs Spastic gait Impaired vibratory sensation Lower limb muscle weakness -Pure or uncomplicated Spasticity, lower limb -Lower limb amyotrophy Walking aids Show more (+6) |
n.a.
|
|
Yes
|
n.a.
|
O
|
AUS
|
20
|
54
|
n.a.
|
Abnormality of the bladder
-Pure or uncomplicated Spasticity, lower limb Walking aids Spastic gait Babinski sign Show more (+3) |
n.a.
|
|
Yes
|
n.a.
|
O
|
AUS
|
4
|
73
|
n.a.
|
-Lower limb amyotrophy
Lower limb muscle weakness Walking aids Spastic gait Hyperreflexia in upper limbs Impaired vibratory sensation Abnormality of the bladder Spasticity, lower limb Babinski sign -Pure or uncomplicated Show more (+7) |
n.a.
|
|
Yes
|
n.a.
|
O
|
AUS
|
41
|
65
|
n.a.
|
Lower limb muscle weakness
Hyperreflexia in upper limbs Spastic gait Walking aids Wheelchair -Pure or uncomplicated Babinski sign Muscle weakness, upper limb Spasticity, lower limb Show more (+6) |
n.a.
|
|
Yes
|
n.a.
|
O
|
AUS
|
2
|
48
|
n.a.
|
Babinski sign
Impaired vibratory sensation Wheelchair Spastic gait Spasticity, lower limb Muscle weakness, upper limb Walking aids Lower limb muscle weakness Hyperreflexia in upper limbs Abnormality of the bladder Show more (+7) |
n.a.
|
|
Yes
|
n.a.
|
O
|
AUS
|
2
|
60
|
n.a.
|
Abnormality of the bladder
Impaired vibratory sensation Spasticity, lower limb -Pure or uncomplicated Lower limb muscle weakness Babinski sign Hyperreflexia in upper limbs Spastic gait Walking aids Show more (+6) |
n.a.
|
|
Yes
|
n.a.
|
O
|
AUS
|
n.a.
|
55
|
n.a.
|
Walking aids
Babinski sign -Pure or uncomplicated Impaired vibratory sensation Hyperreflexia in upper limbs Lower limb muscle weakness Spastic gait Spasticity, lower limb Abnormality of the bladder Show more (+6) |
n.a.
|
|
Yes
|
n.a.
|
O
|
AUS
|
32
|
38
|
n.a.
|
Spasticity, lower limb
Spastic gait Hyperreflexia in upper limbs -Pure or uncomplicated Show more (+1) |
n.a.
|
|
Yes
|
n.a.
|
O
|
AUS
|
10
|
48
|
n.a.
|
Lower limb muscle weakness
Impaired vibratory sensation Walking aids Hyperreflexia in upper limbs Abnormality of the bladder Babinski sign Spasticity, upper limb Spastic gait Ataxia, limb Spasticity, lower limb Show more (+7) |
n.a.
|
|
Yes
|
n.a.
|
O
|
AUS
|
n.a.
|
n.a.
|
n.a.
|
-Pure or uncomplicated
Spastic gait Spasticity, lower limb Lower limb muscle weakness Hyperreflexia in upper limbs -Lower limb amyotrophy Babinski sign Walking aids Show more (+5) |
n.a.
|