Proukakis, 2002: Overview of all reported HSP-SPAST patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
n.a.
|
n.a.
|
n.a.
|
16
|
47
|
No
|
n.a.
|
||
No
|
n.a.
|
n.a.
|
n.a.
|
30
|
71
|
No
|
Abnormality of the bladder
Spastic gait Spasticity, lower limb Lower limb muscle weakness Babinski sign Show more (+2) |
n.a.
|
|
No
|
n.a.
|
n.a.
|
GBR
|
27
|
56
|
No
|
n.a.
|
||
Yes
|
n.a.
|
n.a.
|
GBR
|
45
|
60
|
No
|
Hyperreflexia in upper limbs
Walking aids Babinski sign Abnormality of the bladder Spasticity, lower limb Lower limb muscle weakness Spastic gait Show more (+4) |
n.a.
|
|
No
|
n.a.
|
n.a.
|
GBR
|
25
|
43
|
No
|
Spastic gait
Impaired vibratory sensation Walking aids Spasticity, lower limb Babinski sign Show more (+2) |
n.a.
|
|
No
|
n.a.
|
n.a.
|
GBR
|
35
|
72
|
No
|
Inability to walk
Wheelchair Hyperreflexia in upper limbs Babinski sign Spasticity, lower limb Spastic gait Lower limb muscle weakness Impaired vibratory sensation Show more (+5) |
n.a.
|
|
No
|
n.a.
|
n.a.
|
n.a.
|
16
|
42
|
No
|
Spastic gait
Spasticity, lower limb Lower limb muscle weakness |
n.a.
|
|
No
|
n.a.
|
n.a.
|
n.a.
|
20
|
37
|
No
|
Spasticity, lower limb
Spastic gait Lower limb muscle weakness |
n.a.
|
|
No
|
n.a.
|
n.a.
|
GBR
|
40
|
63
|
No
|
Hyperreflexia in upper limbs
Impaired vibratory sensation Spasticity, lower limb Babinski sign Spastic gait Lower limb muscle weakness Abnormality of the bladder Nystagmus Wheelchair Ataxia, limb Show more (+7) |
n.a.
|
|
No
|
n.a.
|
n.a.
|
n.a.
|
35
|
40
|
No
|
Spastic gait
Spasticity, lower limb |
n.a.
|