Chamard, 2016: Overview of all reported HSP-SPAST patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♀
|
n.a.
|
n.a.
|
40
|
44
|
n.a.
|
Spastic gait
Cognitive impairment |
n.a.
|
|
No
|
♂
|
n.a.
|
n.a.
|
30
|
43
|
n.a.
|
Cognitive impairment
Spastic gait |
n.a.
|
|
Yes
|
♂
|
n.a.
|
n.a.
|
45
|
64
|
n.a.
|
Spastic gait
Cognitive impairment Walking aids |
n.a.
|
|
No
|
♂
|
n.a.
|
n.a.
|
44
|
50
|
n.a.
|
Cognitive impairment
Spastic gait |
n.a.
|
|
Yes
|
♀
|
n.a.
|
n.a.
|
20
|
54
|
n.a.
|
Spastic gait
Cognitive impairment |
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
12
|
45
|
n.a.
|
Walking aids
Spastic gait Cognitive impairment |
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
38
|
50
|
n.a.
|
Spastic gait
Cognitive impairment Walking aids |
n.a.
|
|
Yes
|
♀
|
n.a.
|
n.a.
|
42
|
50
|
n.a.
|
Spastic gait
Cognitive impairment |
n.a.
|