Ivanova, 2007: Overview of all reported HSP-ATL1 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
n.a.
|
C
|
BEL
|
2
|
25
|
n.a.
|
Spasticity, lower limb
Babinski sign -Pure or uncomplicated Lower limb muscle weakness Spastic gait -Lower limb amyotrophy Show more (+3) |
Spastic gait
|
|
No
|
n.a.
|
C
|
BGR
|
1
|
12
|
n.a.
|
-Pure or uncomplicated
Lower limb muscle weakness Walking aids Spasticity, lower limb Babinski sign Show more (+2) |
n.a.
|
|
No
|
n.a.
|
C
|
BGR
|
5
|
39
|
n.a.
|
-Pure or uncomplicated
Babinski sign Spasticity, lower limb Lower limb muscle weakness Show more (+1) |
n.a.
|
|
Yes
|
n.a.
|
C
|
SWE
|
1
|
34
|
n.a.
|
Lower limb muscle weakness
Spasticity, lower limb -Pure or uncomplicated Walking aids -Lower limb amyotrophy Babinski sign Show more (+3) |
n.a.
|
|
No
|
n.a.
|
C
|
AUT
|
10
|
34
|
n.a.
|
Spastic gait
Lower limb muscle weakness Babinski sign Pes cavus Spasticity, lower limb -Lower limb amyotrophy Show more (+3) |
Spastic gait
|
|
No
|
n.a.
|
C
|
BGR
|
5
|
37
|
n.a.
|
Babinski sign
Lower limb muscle weakness -Pure or uncomplicated Spasticity, lower limb Show more (+1) |
n.a.
|
|
No
|
n.a.
|
C
|
AUT
|
10
|
20
|
n.a.
|
-Pure or uncomplicated
-Lower limb amyotrophy Spastic gait |
Spastic gait
|
|
Yes
|
♀
|
C
|
BEL
|
1
|
41
|
n.a.
|
-Pure or uncomplicated
Hyperreflexia in upper limbs Babinski sign -Lower limb amyotrophy Walking aids Spasticity, lower limb Spastic gait Lower limb muscle weakness Show more (+5) |
Spastic gait
|
|
No
|
n.a.
|
C
|
BGR
|
2
|
32
|
n.a.
|
Walking aids
Spasticity, lower limb Lower limb muscle weakness Babinski sign -Pure or uncomplicated Tip-toe gait Show more (+3) |
Tip-toe gait
|
|
No
|
n.a.
|
C
|
BEL
|
1
|
9
|
n.a.
|
Spastic gait
|