Sauter, 2004: Overview of all reported HSP-ATL1 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
♀
|
C
|
n.a.
|
3
|
5
|
n.a.
|
Spastic gait
Spasticity, lower limb -Pure or uncomplicated |
n.a.
|
|
Yes
|
♀
|
C
|
n.a.
|
3
|
37
|
n.a.
|
Spastic gait
Lower limb muscle weakness -Pure or uncomplicated Spasticity, lower limb Babinski sign Show more (+2) |
n.a.
|
|
No
|
♀
|
C
|
n.a.
|
n.a.
|
n.a.
|
n.a.
|
Walking aids
-Pure or uncomplicated Lower limb muscle weakness Spasticity, lower limb Hyperreflexia in upper limbs Cognitive impairment Spastic gait Show more (+4) |
n.a.
|
|
Yes
|
♀
|
C
|
n.a.
|
n.a.
|
38
|
n.a.
|
-Pure or uncomplicated
Lower limb muscle weakness Spasticity, lower limb Babinski sign Spastic gait Show more (+2) |
n.a.
|
|
Yes
|
♂
|
C
|
n.a.
|
1
|
8
|
No
|
Lower limb muscle weakness
-Pure or uncomplicated Babinski sign Spasticity, lower limb Show more (+1) |
n.a.
|
|
Yes
|
♀
|
C
|
n.a.
|
55
|
n.a.
|
No
|
-Pure or uncomplicated
Impaired vibratory sensation Spasticity, lower limb Spastic gait Lower limb muscle weakness Abnormality of the bladder Babinski sign Show more (+4) |
n.a.
|
|
Yes
|
♂
|
C
|
n.a.
|
3
|
53
|
No
|
Abnormality of the bladder
-Pure or uncomplicated Lower limb muscle weakness Walking aids Babinski sign Spasticity, lower limb Wheelchair Show more (+4) |
n.a.
|
|
No
|
♂
|
C
|
n.a.
|
n.a.
|
n.a.
|
n.a.
|
Spasticity, lower limb
Lower limb muscle weakness Spastic gait -Pure or uncomplicated Babinski sign Show more (+2) |
n.a.
|
|
No
|
♂
|
C
|
n.a.
|
3
|
n.a.
|
No
|
Lower limb muscle weakness
Spasticity, lower limb -Pure or uncomplicated Babinski sign Show more (+1) |
n.a.
|