Willkomm, 2016: Overview of all reported HSP-ATL1 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
♂
|
B
|
n.a.
|
2
|
7
|
n.a.
|
n.a.
|
||
Yes
|
♂
|
B
|
n.a.
|
8
|
15
|
n.a.
|
Impaired vibratory sensation
Lower limb muscle weakness Peripheral neuropathy on nerve conduction studies Walking aids Cognitive impairment Muscle weakness, upper limb Upper limb amyotrophy Spasticity, lower limb Hyperreflexia in upper limbs Spastic gait Abnormality of the bladder Ataxia, limb Tip-toe gait Babinski sign Show more (+11) |
n.a.
|
|
No
|
♂
|
B
|
n.a.
|
1
|
3
|
n.a.
|
n.a.
|