Yes

♂

C

BRA

n.a.

46

Yes

Brain calcification
-Motor

n.a.

p.Leu119Pro: het

No

♂

C

FRA

63

63

Yes

-Motor
Brain calcification
Cognitive decline
Psychotic sign/sympt.
Parkinsonism
Show more (+2)

Psychotic sign/sympt.

p.*242Tyrext*89: het

No

♀

C

n.a.

n.a.

38

Yes

-Motor
Headache

n.a.

p.Met1?: het

No

♂

C

SRB

n.a.

n.a.

Yes

-Motor
Brain calcification
NMS parkinsonism
Athetosis
Dyskinesia
Anxiety
Chorea
Show more (+4)

Dyskinesia

p.Gln145*: het

No

♂

C

SRB

44

47

Yes

Dyskinesia
Brain calcification
Tremor (any or unspecified)
-Motor
Show more (+1)

Dyskinesia

p.Gln145*: het

No

♀

C

SRB

42

43

Yes

-Motor
Cerebellar signs
Chorea
Dyskinesia
NMS parkinsonism
Depression
Brain calcification
Cognitive decline
Anxiety
Show more (+6)

Anxiety

p.Gln145*: het

Yes

♀

C

n.a.

16

30

Yes

Migraine (any subclass)
Parkinsonism
Speech disturbance
Brain calcification
Tremor (any or unspecified)
Depression
Chorea
PKD
Cognitive decline
-Motor
Headache
Show more (+8)

Migraine (any subclass)

p.Leu9Arg: het

No

♀

C

n.a.

n.a.

15

Yes

Cognitive decline
Migraine (any subclass)
Dystonia
-Motor
Headache
Brain calcification
Show more (+3)

n.a.

p.Met1?: het

Yes

♀

C

n.a.

n.a.

34

Yes

-Motor
Headache
Dystonia
Brain calcification
Show more (+1)

n.a.

p.Met1?: het

Yes

♂

C

SRB

36

41

Yes

Depression
Cognitive decline
Dyskinesia
Brain calcification
Parkinsonism
Psychotic sign/sympt.
Ataxia
-Motor
NMS parkinsonism
Show more (+6)

Ataxia

p.Gln145*: het