Graves, 2010: Overview of all reported PxMD-KCNA1 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
♀
|
n.a.
|
n.a.
|
16
|
39
|
Yes
|
-Tremor (ictal)
Ataxia, limb Dizziness Ataxia, limb (ictal) Ataxia Ataxia (ictal) Tremor (any or unspecified) Dysarthria Dysarthria (ictal) Show more (+6) |
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
12
|
42
|
Yes
|
Ataxia
Dysarthria (ictal) Gait ataxia -Gait ataxia (ictal) Ataxia (ictal) Dysarthria Dizziness Show more (+4) |
n.a.
|
|
Yes
|
♂
|
n.a.
|
n.a.
|
6
|
23
|
Yes
|
Ataxia, limb (ictal)
Muscle weakness Visual blurring Gait ataxia Myokymia -Gait ataxia (ictal) -Muscle weakness (ictal) Dysarthria Ataxia (ictal) Dysarthria (ictal) -Visual blurring (ictal) Ataxia, limb Ataxia Show more (+10) |
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
5
|
50
|
Yes
|
Dysarthria (ictal)
Gait ataxia -Muscle weakness (ictal) Dysarthria Muscle weakness -Visual blurring (ictal) Vertigo Ataxia, limb Tremor (any or unspecified) Visual blurring Nausea Ataxia (interictal) Headache (ictal) Ataxia, limb (ictal) -Gait ataxia (ictal) Ataxia Myokymia Nausea (ictal) -Tremor (ictal) Dysarthria (interictal) Ataxia (ictal) Headache Vertigo (ictal) Show more (+20) |
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
8
|
21
|
Yes
|
Ataxia (ictal)
Dysarthria (ictal) Visual blurring -Muscle weakness (ictal) Ataxia Ataxia, limb (ictal) -Gait ataxia (ictal) Ataxia, limb Dysarthria Gait ataxia -Visual blurring (ictal) Muscle weakness Show more (+9) |
n.a.
|
|
No
|
♂
|
n.a.
|
n.a.
|
1
|
14
|
Yes
|
Ataxia (ictal)
-Gait ataxia (ictal) Ataxia Dizziness Dysarthria (ictal) Dysarthria Gait ataxia Show more (+4) |
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
14
|
n.a.
|
Yes
|
Dysarthria
Ataxia, limb (ictal) -Gait ataxia (ictal) Nausea (ictal) Dysarthria (ictal) Myokymia -Muscle weakness (ictal) Ataxia Muscle weakness Dizziness Nausea Ataxia, limb Ataxia (ictal) Gait ataxia Show more (+11) |
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
12
|
35
|
Yes
|
Muscle weakness
Dysarthria (ictal) -Tremor (ictal) Gait ataxia Myokymia Vertigo (ictal) Tremor (any or unspecified) -Muscle weakness (ictal) Ataxia Dizziness -Gait ataxia (ictal) Ataxia (ictal) Vertigo Dysarthria Show more (+11) |
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
15
|
36
|
Yes
|
Ataxia, limb
Vertigo (ictal) -Muscle weakness (ictal) Gait ataxia Ataxia (ictal) Dysarthria Vertigo Muscle weakness Headache Myokymia -Gait ataxia (ictal) Ataxia Ataxia, limb (ictal) Nausea (ictal) Dizziness Nausea Dysarthria (ictal) Headache (ictal) Show more (+15) |
n.a.
|
|
Yes
|
♀
|
n.a.
|
n.a.
|
12
|
16
|
Yes
|
-Muscle weakness (ictal)
Myokymia Ataxia, limb (ictal) Dysarthria (ictal) Dysarthria -Gait ataxia (ictal) Ataxia (ictal) Muscle weakness Ataxia, limb Nausea Dizziness Nausea (ictal) Ataxia Gait ataxia Show more (+11) |
n.a.
|