Graves, 2010: Overview of all reported PxMD-KCNA1 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
♀
|
n.a.
|
n.a.
|
16
|
39
|
Yes
|
Ataxia, limb
Ataxia (ictal) Dizziness Dysarthria (ictal) -Tremor (ictal) Ataxia, limb (ictal) Ataxia Dysarthria Tremor (any or unspecified) Show more (+6) |
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
12
|
42
|
Yes
|
-Gait ataxia (ictal)
Ataxia (ictal) Dysarthria (ictal) Dizziness Ataxia Dysarthria Gait ataxia Show more (+4) |
n.a.
|
|
Yes
|
♂
|
n.a.
|
n.a.
|
6
|
23
|
Yes
|
Dysarthria (ictal)
Gait ataxia Ataxia, limb (ictal) -Gait ataxia (ictal) Ataxia (ictal) Muscle weakness -Visual blurring (ictal) Dysarthria Myokymia Ataxia Ataxia, limb Visual blurring -Muscle weakness (ictal) Show more (+10) |
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
5
|
50
|
Yes
|
Tremor (any or unspecified)
Ataxia, limb (ictal) Muscle weakness Ataxia (ictal) Ataxia, limb -Muscle weakness (ictal) Ataxia Headache Nausea Nausea (ictal) -Gait ataxia (ictal) Vertigo Myokymia Dysarthria (interictal) Dysarthria Vertigo (ictal) -Visual blurring (ictal) Visual blurring Ataxia (interictal) Gait ataxia Dysarthria (ictal) Headache (ictal) -Tremor (ictal) Show more (+20) |
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
8
|
21
|
Yes
|
Dysarthria
Muscle weakness -Visual blurring (ictal) Visual blurring -Gait ataxia (ictal) Ataxia Ataxia, limb Gait ataxia -Muscle weakness (ictal) Ataxia (ictal) Dysarthria (ictal) Ataxia, limb (ictal) Show more (+9) |
n.a.
|
|
No
|
♂
|
n.a.
|
n.a.
|
1
|
14
|
Yes
|
Ataxia
Ataxia (ictal) Dysarthria (ictal) Dizziness Dysarthria Gait ataxia -Gait ataxia (ictal) Show more (+4) |
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
14
|
n.a.
|
Yes
|
Myokymia
Nausea (ictal) Muscle weakness Nausea Ataxia Ataxia, limb (ictal) Ataxia, limb Dizziness Dysarthria Dysarthria (ictal) -Muscle weakness (ictal) Ataxia (ictal) -Gait ataxia (ictal) Gait ataxia Show more (+11) |
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
12
|
35
|
Yes
|
-Gait ataxia (ictal)
Ataxia (ictal) Dysarthria Tremor (any or unspecified) Vertigo Myokymia Gait ataxia -Tremor (ictal) Ataxia Vertigo (ictal) Dizziness Muscle weakness Dysarthria (ictal) -Muscle weakness (ictal) Show more (+11) |
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
15
|
36
|
Yes
|
Nausea (ictal)
Dysarthria Headache (ictal) -Muscle weakness (ictal) Dizziness Ataxia, limb (ictal) Myokymia Gait ataxia Vertigo (ictal) Vertigo Ataxia (ictal) -Gait ataxia (ictal) Ataxia Ataxia, limb Headache Dysarthria (ictal) Muscle weakness Nausea Show more (+15) |
n.a.
|
|
Yes
|
♀
|
n.a.
|
n.a.
|
12
|
16
|
Yes
|
Ataxia, limb
Nausea Dysarthria Myokymia Muscle weakness Ataxia (ictal) Dysarthria (ictal) Nausea (ictal) -Muscle weakness (ictal) Gait ataxia Dizziness -Gait ataxia (ictal) Ataxia Ataxia, limb (ictal) Show more (+11) |
n.a.
|