Graves, 2010: Overview of all reported PxMD-KCNA1 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
♀
|
n.a.
|
n.a.
|
16
|
39
|
Yes
|
Dysarthria
Ataxia, limb (ictal) -Tremor (ictal) Ataxia Dysarthria (ictal) Tremor (any or unspecified) Ataxia, limb Ataxia (ictal) Dizziness Show more (+6) |
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
12
|
42
|
Yes
|
Dizziness
-Gait ataxia (ictal) Ataxia (ictal) Dysarthria (ictal) Dysarthria Ataxia Gait ataxia Show more (+4) |
n.a.
|
|
Yes
|
♂
|
n.a.
|
n.a.
|
6
|
23
|
Yes
|
Visual blurring
Ataxia, limb Myokymia -Visual blurring (ictal) -Gait ataxia (ictal) Gait ataxia Dysarthria Ataxia (ictal) Ataxia, limb (ictal) -Muscle weakness (ictal) Ataxia Dysarthria (ictal) Muscle weakness Show more (+10) |
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
5
|
50
|
Yes
|
-Visual blurring (ictal)
Ataxia (ictal) Dysarthria (interictal) Gait ataxia Nausea Tremor (any or unspecified) Ataxia -Gait ataxia (ictal) Ataxia, limb Vertigo Dysarthria Headache Dysarthria (ictal) Ataxia, limb (ictal) -Muscle weakness (ictal) Muscle weakness Vertigo (ictal) Headache (ictal) Ataxia (interictal) Nausea (ictal) Visual blurring -Tremor (ictal) Myokymia Show more (+20) |
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
8
|
21
|
Yes
|
Muscle weakness
Ataxia, limb -Visual blurring (ictal) Ataxia, limb (ictal) Dysarthria Gait ataxia -Muscle weakness (ictal) Ataxia -Gait ataxia (ictal) Dysarthria (ictal) Visual blurring Ataxia (ictal) Show more (+9) |
n.a.
|
|
No
|
♂
|
n.a.
|
n.a.
|
1
|
14
|
Yes
|
Ataxia
Gait ataxia Dizziness Ataxia (ictal) Dysarthria Dysarthria (ictal) -Gait ataxia (ictal) Show more (+4) |
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
14
|
n.a.
|
Yes
|
Dizziness
Ataxia (ictal) Nausea -Gait ataxia (ictal) -Muscle weakness (ictal) Nausea (ictal) Ataxia Ataxia, limb (ictal) Dysarthria (ictal) Muscle weakness Ataxia, limb Gait ataxia Dysarthria Myokymia Show more (+11) |
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
12
|
35
|
Yes
|
-Tremor (ictal)
-Gait ataxia (ictal) Dizziness Dysarthria (ictal) -Muscle weakness (ictal) Ataxia (ictal) Dysarthria Gait ataxia Vertigo Ataxia Muscle weakness Vertigo (ictal) Myokymia Tremor (any or unspecified) Show more (+11) |
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
15
|
36
|
Yes
|
Ataxia (ictal)
-Muscle weakness (ictal) Muscle weakness Vertigo (ictal) Ataxia Dysarthria (ictal) Dizziness -Gait ataxia (ictal) Ataxia, limb (ictal) Nausea Vertigo Headache Nausea (ictal) Dysarthria Headache (ictal) Ataxia, limb Gait ataxia Myokymia Show more (+15) |
n.a.
|
|
Yes
|
♀
|
n.a.
|
n.a.
|
12
|
16
|
Yes
|
Dysarthria
-Gait ataxia (ictal) Gait ataxia Muscle weakness Myokymia Ataxia, limb (ictal) Dysarthria (ictal) Ataxia, limb Nausea Ataxia (ictal) Ataxia Dizziness -Muscle weakness (ictal) Nausea (ictal) Show more (+11) |
n.a.
|