Graves, 2010: Overview of all reported PxMD-KCNA1 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
♀
|
n.a.
|
n.a.
|
16
|
39
|
Yes
|
Ataxia
Ataxia (ictal) Dysarthria Tremor (any or unspecified) -Tremor (ictal) Ataxia, limb (ictal) Dysarthria (ictal) Ataxia, limb Dizziness Show more (+6) |
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
12
|
42
|
Yes
|
Ataxia
Dysarthria Dysarthria (ictal) Gait ataxia -Gait ataxia (ictal) Ataxia (ictal) Dizziness Show more (+4) |
n.a.
|
|
Yes
|
♂
|
n.a.
|
n.a.
|
6
|
23
|
Yes
|
-Gait ataxia (ictal)
Visual blurring Gait ataxia Ataxia (ictal) Ataxia, limb Myokymia Muscle weakness Ataxia -Visual blurring (ictal) Ataxia, limb (ictal) Dysarthria (ictal) -Muscle weakness (ictal) Dysarthria Show more (+10) |
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
5
|
50
|
Yes
|
Dysarthria
Headache (ictal) Nausea (ictal) Nausea Dysarthria (interictal) Ataxia (interictal) Gait ataxia Ataxia (ictal) -Muscle weakness (ictal) Ataxia, limb (ictal) Muscle weakness Visual blurring -Tremor (ictal) Headache Ataxia Tremor (any or unspecified) Vertigo (ictal) Ataxia, limb Dysarthria (ictal) -Gait ataxia (ictal) -Visual blurring (ictal) Myokymia Vertigo Show more (+20) |
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
8
|
21
|
Yes
|
Dysarthria (ictal)
Visual blurring -Muscle weakness (ictal) -Gait ataxia (ictal) Ataxia (ictal) Ataxia, limb Gait ataxia Muscle weakness -Visual blurring (ictal) Dysarthria Ataxia Ataxia, limb (ictal) Show more (+9) |
n.a.
|
|
No
|
♂
|
n.a.
|
n.a.
|
1
|
14
|
Yes
|
Dysarthria (ictal)
Ataxia (ictal) Gait ataxia Ataxia Dizziness Dysarthria -Gait ataxia (ictal) Show more (+4) |
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
14
|
n.a.
|
Yes
|
Gait ataxia
Dizziness Dysarthria Nausea Myokymia Ataxia, limb (ictal) Ataxia (ictal) -Gait ataxia (ictal) Dysarthria (ictal) Ataxia, limb Nausea (ictal) Ataxia -Muscle weakness (ictal) Muscle weakness Show more (+11) |
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
12
|
35
|
Yes
|
Gait ataxia
Vertigo (ictal) Ataxia Dysarthria -Gait ataxia (ictal) Myokymia -Tremor (ictal) Tremor (any or unspecified) Vertigo Dizziness Muscle weakness Dysarthria (ictal) -Muscle weakness (ictal) Ataxia (ictal) Show more (+11) |
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
15
|
36
|
Yes
|
Dysarthria (ictal)
-Gait ataxia (ictal) Ataxia (ictal) Ataxia Ataxia, limb (ictal) Vertigo (ictal) Headache Vertigo Ataxia, limb Dizziness Nausea Dysarthria Headache (ictal) Myokymia Gait ataxia Nausea (ictal) Muscle weakness -Muscle weakness (ictal) Show more (+15) |
n.a.
|
|
Yes
|
♀
|
n.a.
|
n.a.
|
12
|
16
|
Yes
|
-Gait ataxia (ictal)
Nausea Dizziness Nausea (ictal) Ataxia, limb Ataxia, limb (ictal) Muscle weakness Myokymia -Muscle weakness (ictal) Ataxia Dysarthria (ictal) Ataxia (ictal) Dysarthria Gait ataxia Show more (+11) |
n.a.
|