Romaniello, 2010: Overview of all reported PxMD-CACNA1A patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♀
|
n.a.
|
n.a.
|
n.a.
|
n.a.
|
n.a.
|
-Limb ataxia (interictal)
Tremor (any or unspecified) -Tremor (ictal) Ataxia, limb -Muscle weakness (ictal) Dysarthria (ictal) Dysarthria Ataxia Muscle weakness Show more (+6) |
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
15
|
n.a.
|
n.a.
|
Migraine
Physical stress trigger Emotional stress trigger Ataxia Headache Ataxia, limb Nausea (ictal) Tremor (any or unspecified) Dysarthria Vertigo (ictal) Muscle weakness Dysarthria (ictal) Vertigo -Tremor (ictal) -Muscle weakness (ictal) Nausea Cerebellar atrophy Ataxia (ictal) Ataxia, limb (ictal) Show more (+16) |
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
6
|
12
|
n.a.
|
-Tremor (interictal)
Muscular hypotonia Ataxia Headache Seizures Ataxia (interictal) Tremor (any or unspecified) Dysarthria (interictal) Cerebellar atrophy -Limb ataxia (interictal) Dysarthria Muscular hypotonia (interictal) Ataxia, limb Extensor plantar response Show more (+11) |
Tremor (any or unspecified)
Dysarthria |