Subramony, 2003: Overview of all reported PxMD-CACNA1A patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
♀
|
C
|
USA
|
n.a.
|
77
|
n.a.
|
Vomiting
Emotional stress trigger Ataxia (interictal) Headache (ictal) Muscle weakness -Limb ataxia (interictal) Dysarthria Ataxia Physical stress trigger -Muscle weakness (ictal) Nausea (ictal) Headache Vomiting (ictal) Cerebellar atrophy Nystagmus Gait ataxia Nystagmus (interictal) -Gait ataxia (interictal) Heat trigger Nausea Ataxia, limb Dysarthria (interictal) Show more (+19) |
n.a.
|
|
No
|
♀
|
C
|
USA
|
12
|
50
|
n.a.
|
Nausea
-Gait ataxia (interictal) Vertigo Nystagmus Dysmetric saccades Diplopia (ictal) Vomiting Square wave jerks -Muscle weakness (ictal) Vomiting (ictal) Muscle weakness Slow saccades Nausea (ictal) Diplopia Vertigo (ictal) Headache (ictal) Headache Nystagmus (interictal) Ataxia, limb Emotional stress trigger -Limb ataxia (interictal) Gait ataxia Ataxia (interictal) Heat trigger Ataxia Show more (+22) |
n.a.
|
|
Yes
|
♀
|
C
|
USA
|
6
|
75
|
n.a.
|
Gait ataxia
Vertigo (ictal) Ataxia, limb Nystagmus Emotional stress trigger Dysarthria (interictal) Ataxia (ictal) -Gait ataxia (interictal) -Muscle weakness (ictal) Ataxia -Limb ataxia (interictal) Dysmetric saccades Heat trigger Square wave jerks Muscle weakness Vertigo Ataxia (interictal) Slow saccades Headache Dysarthria Headache (ictal) Nystagmus (interictal) Sudden movment trigger Show more (+20) |
n.a.
|
|
No
|
♂
|
C
|
USA
|
13
|
31
|
n.a.
|
Vertigo
Nausea (ictal) Nausea Square wave jerks Heat trigger Sudden movment trigger Vomiting (ictal) Dysmetric saccades Vomiting Muscle weakness -Muscle weakness (ictal) Slow saccades Vertigo (ictal) Emotional stress trigger Show more (+11) |
n.a.
|
|
No
|
♂
|
C
|
USA
|
7
|
51
|
n.a.
|
-Gait ataxia (interictal)
Nystagmus (interictal) Nausea Nystagmus Vertigo Heat trigger Nausea (ictal) Emotional stress trigger Vertigo (ictal) Ataxia Ataxia, limb Dysarthria (interictal) -Limb ataxia (interictal) Caffeine trigger Vomiting (ictal) Dysarthria Gait ataxia Headache Headache (ictal) Vomiting Ataxia (interictal) Show more (+18) |
n.a.
|
|
No
|
♂
|
C
|
USA
|
9
|
33
|
n.a.
|
Vertigo
Vomiting (ictal) Vertigo (ictal) Headache Nystagmus (interictal) Nystagmus Vomiting Heat trigger Headache (ictal) Nausea (ictal) Nausea Emotional stress trigger Muscle weakness -Muscle weakness (ictal) Show more (+11) |
n.a.
|
|
No
|
♂
|
C
|
USA
|
n.a.
|
45
|
n.a.
|
Vomiting
Ataxia (interictal) Nystagmus (interictal) Vertigo Nystagmus Ataxia Headache (ictal) Heat trigger Vomiting (ictal) Gait ataxia Vertigo (ictal) -Gait ataxia (interictal) Headache Nausea Nausea (ictal) Emotional stress trigger Show more (+13) |
n.a.
|