Subramony, 2003: Overview of all reported PxMD-CACNA1A patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
♀
|
C
|
USA
|
n.a.
|
77
|
n.a.
|
Heat trigger
Vomiting -Muscle weakness (ictal) Headache Ataxia Physical stress trigger -Limb ataxia (interictal) Vomiting (ictal) -Gait ataxia (interictal) Ataxia, limb Gait ataxia Ataxia (interictal) Nausea (ictal) Nausea Nystagmus Cerebellar atrophy Headache (ictal) Dysarthria Nystagmus (interictal) Dysarthria (interictal) Emotional stress trigger Muscle weakness Show more (+19) |
n.a.
|
|
No
|
♀
|
C
|
USA
|
12
|
50
|
n.a.
|
Headache (ictal)
-Muscle weakness (ictal) Square wave jerks Vomiting (ictal) Nystagmus Nausea (ictal) Emotional stress trigger Dysmetric saccades Muscle weakness Vertigo Slow saccades Nystagmus (interictal) Ataxia (interictal) Vomiting Headache -Gait ataxia (interictal) Ataxia Diplopia (ictal) Ataxia, limb Gait ataxia Nausea Diplopia Heat trigger Vertigo (ictal) -Limb ataxia (interictal) Show more (+22) |
n.a.
|
|
Yes
|
♀
|
C
|
USA
|
6
|
75
|
n.a.
|
Dysarthria
Ataxia, limb Ataxia (interictal) -Muscle weakness (ictal) Sudden movment trigger Muscle weakness Vertigo (ictal) Dysarthria (interictal) -Gait ataxia (interictal) -Limb ataxia (interictal) Nystagmus (interictal) Nystagmus Dysmetric saccades Gait ataxia Vertigo Ataxia (ictal) Headache (ictal) Ataxia Heat trigger Emotional stress trigger Headache Slow saccades Square wave jerks Show more (+20) |
n.a.
|
|
No
|
♂
|
C
|
USA
|
13
|
31
|
n.a.
|
Emotional stress trigger
Dysmetric saccades Muscle weakness Vertigo (ictal) Vomiting Nausea Slow saccades Vomiting (ictal) Nausea (ictal) Vertigo Heat trigger Square wave jerks -Muscle weakness (ictal) Sudden movment trigger Show more (+11) |
n.a.
|
|
No
|
♂
|
C
|
USA
|
7
|
51
|
n.a.
|
-Limb ataxia (interictal)
Dysarthria (interictal) Vomiting Dysarthria Nystagmus (interictal) Heat trigger Gait ataxia -Gait ataxia (interictal) Nausea (ictal) Caffeine trigger Vertigo (ictal) Headache Vertigo Ataxia (interictal) Emotional stress trigger Nausea Ataxia, limb Ataxia Headache (ictal) Vomiting (ictal) Nystagmus Show more (+18) |
n.a.
|
|
No
|
♂
|
C
|
USA
|
9
|
33
|
n.a.
|
Nausea
Nausea (ictal) Vertigo Headache -Muscle weakness (ictal) Vomiting (ictal) Headache (ictal) Heat trigger Vertigo (ictal) Nystagmus (interictal) Nystagmus Muscle weakness Emotional stress trigger Vomiting Show more (+11) |
n.a.
|
|
No
|
♂
|
C
|
USA
|
n.a.
|
45
|
n.a.
|
Nausea
Nystagmus (interictal) Vertigo (ictal) Ataxia (interictal) Heat trigger Gait ataxia Emotional stress trigger Vomiting (ictal) Vertigo Headache (ictal) Nausea (ictal) Vomiting Headache Nystagmus -Gait ataxia (interictal) Ataxia Show more (+13) |
n.a.
|