Di Fonzo, 2009: Overview of all reported PARK-FBXO7 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
♂
|
C
|
ITA
|
13
|
n.a.
|
n.a.
|
Motor fluctuations
Dysarthria/anarthria Saccadic abnormalities Tremor, action Rigidity Dyskinesia Spasticity/pyramidal signs Dystonia Incontinence Bradykinesia Behavioral abnormalities NMS parkinsonism Atypical parkinsonism Gaze palsy Tremor at rest Tremor (any or unspecified) Parkinsonism Dysphagia Postural instability Show more (+16) |
Rigidity
Tremor (any or unspecified) |
|
Yes
|
♀
|
C
|
ITA
|
10
|
n.a.
|
n.a.
|
Motor fluctuations
Incontinence Tremor, action Parkinsonism Micrographia Tremor (any or unspecified) Dyskinesia Atypical parkinsonism Dystonia Bradykinesia Dysphagia Postural instability Tremor at rest NMS parkinsonism Dysarthria/anarthria Rigidity Behavioral abnormalities Spasticity/pyramidal signs Show more (+15) |
Tremor (any or unspecified)
Rigidity |
|
Yes
|
♂
|
C
|
NLD
|
19
|
n.a.
|
n.a.
|
Spasticity/pyramidal signs
Motor fluctuations Parkinsonism Dysphagia Dyskinesia Postural instability Behavioral abnormalities Rigidity Tremor (any or unspecified) Bradykinesia Atypical parkinsonism Tremor at rest NMS parkinsonism Tremor, action Show more (+11) |
Behavioral abnormalities
Bradykinesia |
|
No
|
♀
|
C
|
NLD
|
18
|
n.a.
|
n.a.
|
Spasticity/pyramidal signs
Tremor (any or unspecified) Bradykinesia Behavioral abnormalities Dyskinesia Saccadic abnormalities Tremor, action Rigidity Atypical parkinsonism Gaze palsy Postural instability Parkinsonism Motor fluctuations Show more (+10) |
Tremor (any or unspecified)
Behavioral abnormalities |