Di Fonzo, 2009: Overview of all reported PARK-FBXO7 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
♂
|
C
|
ITA
|
13
|
n.a.
|
n.a.
|
Gaze palsy
Dyskinesia Dysarthria/anarthria Behavioral abnormalities Saccadic abnormalities Parkinsonism Spasticity/pyramidal signs Rigidity Postural instability Atypical parkinsonism Dystonia NMS parkinsonism Incontinence Dysphagia Tremor (any or unspecified) Motor fluctuations Tremor, action Tremor at rest Bradykinesia Show more (+16) |
Rigidity
Tremor (any or unspecified) |
|
Yes
|
♀
|
C
|
ITA
|
10
|
n.a.
|
n.a.
|
Dyskinesia
Parkinsonism Incontinence Postural instability Bradykinesia Dysphagia Tremor (any or unspecified) NMS parkinsonism Rigidity Dystonia Spasticity/pyramidal signs Micrographia Tremor, action Behavioral abnormalities Tremor at rest Motor fluctuations Dysarthria/anarthria Atypical parkinsonism Show more (+15) |
Tremor (any or unspecified)
Rigidity |
|
Yes
|
♂
|
C
|
NLD
|
19
|
n.a.
|
n.a.
|
Tremor, action
Parkinsonism Behavioral abnormalities NMS parkinsonism Atypical parkinsonism Motor fluctuations Tremor (any or unspecified) Spasticity/pyramidal signs Postural instability Bradykinesia Dyskinesia Tremor at rest Dysphagia Rigidity Show more (+11) |
Behavioral abnormalities
Bradykinesia |
|
No
|
♀
|
C
|
NLD
|
18
|
n.a.
|
n.a.
|
Tremor, action
Atypical parkinsonism Postural instability Behavioral abnormalities Rigidity Tremor (any or unspecified) Spasticity/pyramidal signs Gaze palsy Dyskinesia Motor fluctuations Saccadic abnormalities Parkinsonism Bradykinesia Show more (+10) |
Behavioral abnormalities
Tremor (any or unspecified) |