Di Fonzo, 2009: Overview of all reported PARK-FBXO7 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
♂
|
C
|
ITA
|
13
|
n.a.
|
n.a.
|
Incontinence
Dysarthria/anarthria Atypical parkinsonism Tremor (any or unspecified) Gaze palsy Dyskinesia NMS parkinsonism Rigidity Parkinsonism Postural instability Saccadic abnormalities Tremor at rest Motor fluctuations Dystonia Spasticity/pyramidal signs Behavioral abnormalities Tremor, action Bradykinesia Dysphagia Show more (+16) |
Tremor (any or unspecified)
Rigidity |
|
Yes
|
♀
|
C
|
ITA
|
10
|
n.a.
|
n.a.
|
Tremor, action
Behavioral abnormalities Tremor at rest Parkinsonism Motor fluctuations Dysarthria/anarthria Spasticity/pyramidal signs Tremor (any or unspecified) Incontinence Atypical parkinsonism Dystonia NMS parkinsonism Dyskinesia Bradykinesia Micrographia Postural instability Rigidity Dysphagia Show more (+15) |
Tremor (any or unspecified)
Rigidity |
|
Yes
|
♂
|
C
|
NLD
|
19
|
n.a.
|
n.a.
|
Dysphagia
Motor fluctuations NMS parkinsonism Tremor at rest Postural instability Parkinsonism Tremor (any or unspecified) Rigidity Spasticity/pyramidal signs Atypical parkinsonism Bradykinesia Tremor, action Behavioral abnormalities Dyskinesia Show more (+11) |
Bradykinesia
Behavioral abnormalities |
|
No
|
♀
|
C
|
NLD
|
18
|
n.a.
|
n.a.
|
Dyskinesia
Rigidity Bradykinesia Motor fluctuations Postural instability Saccadic abnormalities Atypical parkinsonism Spasticity/pyramidal signs Behavioral abnormalities Parkinsonism Gaze palsy Tremor (any or unspecified) Tremor, action Show more (+10) |
Behavioral abnormalities
Tremor (any or unspecified) |