Di Fonzo, 2009: Overview of all reported PARK-FBXO7 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
♂
|
C
|
ITA
|
13
|
n.a.
|
n.a.
|
Saccadic abnormalities
Bradykinesia Rigidity Tremor at rest Tremor (any or unspecified) Tremor, action Postural instability Dysphagia Dyskinesia Parkinsonism Atypical parkinsonism Behavioral abnormalities Spasticity/pyramidal signs Dystonia NMS parkinsonism Dysarthria/anarthria Gaze palsy Incontinence Motor fluctuations Show more (+16) |
Rigidity
Tremor (any or unspecified) |
|
Yes
|
♀
|
C
|
ITA
|
10
|
n.a.
|
n.a.
|
NMS parkinsonism
Dyskinesia Postural instability Atypical parkinsonism Motor fluctuations Tremor (any or unspecified) Spasticity/pyramidal signs Micrographia Dysphagia Tremor at rest Incontinence Behavioral abnormalities Bradykinesia Rigidity Tremor, action Dysarthria/anarthria Parkinsonism Dystonia Show more (+15) |
Tremor (any or unspecified)
Rigidity |
|
Yes
|
♂
|
C
|
NLD
|
19
|
n.a.
|
n.a.
|
Bradykinesia
Tremor, action Atypical parkinsonism Dyskinesia Dysphagia Rigidity Parkinsonism NMS parkinsonism Tremor at rest Postural instability Motor fluctuations Spasticity/pyramidal signs Tremor (any or unspecified) Behavioral abnormalities Show more (+11) |
Bradykinesia
Behavioral abnormalities |
|
No
|
♀
|
C
|
NLD
|
18
|
n.a.
|
n.a.
|
Atypical parkinsonism
Bradykinesia Tremor (any or unspecified) Tremor, action Behavioral abnormalities Postural instability Spasticity/pyramidal signs Dyskinesia Parkinsonism Saccadic abnormalities Gaze palsy Rigidity Motor fluctuations Show more (+10) |
Tremor (any or unspecified)
Behavioral abnormalities |