Di Fonzo, 2009: Overview of all reported PARK-FBXO7 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
♂
|
C
|
ITA
|
13
|
n.a.
|
n.a.
|
Parkinsonism
Tremor (any or unspecified) Tremor, action Dysarthria/anarthria Dysphagia Dyskinesia Behavioral abnormalities Motor fluctuations Rigidity NMS parkinsonism Postural instability Gaze palsy Incontinence Tremor at rest Saccadic abnormalities Dystonia Atypical parkinsonism Spasticity/pyramidal signs Bradykinesia Show more (+16) |
Tremor (any or unspecified)
Rigidity |
|
Yes
|
♀
|
C
|
ITA
|
10
|
n.a.
|
n.a.
|
Tremor at rest
Dysarthria/anarthria Incontinence Atypical parkinsonism Micrographia Dyskinesia Behavioral abnormalities Parkinsonism Motor fluctuations Bradykinesia NMS parkinsonism Rigidity Spasticity/pyramidal signs Tremor (any or unspecified) Tremor, action Dystonia Dysphagia Postural instability Show more (+15) |
Rigidity
Tremor (any or unspecified) |
|
Yes
|
♂
|
C
|
NLD
|
19
|
n.a.
|
n.a.
|
Dyskinesia
Atypical parkinsonism Parkinsonism Postural instability Dysphagia Bradykinesia Motor fluctuations Spasticity/pyramidal signs Tremor (any or unspecified) Rigidity Tremor, action NMS parkinsonism Tremor at rest Behavioral abnormalities Show more (+11) |
Bradykinesia
Behavioral abnormalities |
|
No
|
♀
|
C
|
NLD
|
18
|
n.a.
|
n.a.
|
Tremor, action
Saccadic abnormalities Tremor (any or unspecified) Spasticity/pyramidal signs Parkinsonism Motor fluctuations Dyskinesia Bradykinesia Gaze palsy Behavioral abnormalities Atypical parkinsonism Rigidity Postural instability Show more (+10) |
Tremor (any or unspecified)
Behavioral abnormalities |