Di Fonzo, 2009: Overview of all reported PARK-FBXO7 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
♂
|
C
|
ITA
|
13
|
n.a.
|
n.a.
|
Dyskinesia
Postural instability Dysphagia Incontinence Motor fluctuations Bradykinesia Dystonia Spasticity/pyramidal signs Atypical parkinsonism Dysarthria/anarthria NMS parkinsonism Behavioral abnormalities Tremor, action Tremor at rest Rigidity Parkinsonism Gaze palsy Saccadic abnormalities Tremor (any or unspecified) Show more (+16) |
Rigidity
Tremor (any or unspecified) |
|
Yes
|
♀
|
C
|
ITA
|
10
|
n.a.
|
n.a.
|
Bradykinesia
Parkinsonism Dyskinesia Dystonia Micrographia Tremor at rest Motor fluctuations Tremor, action Tremor (any or unspecified) Dysphagia NMS parkinsonism Incontinence Behavioral abnormalities Dysarthria/anarthria Postural instability Spasticity/pyramidal signs Rigidity Atypical parkinsonism Show more (+15) |
Tremor (any or unspecified)
Rigidity |
|
Yes
|
♂
|
C
|
NLD
|
19
|
n.a.
|
n.a.
|
Spasticity/pyramidal signs
Dysphagia Postural instability Behavioral abnormalities Tremor at rest Dyskinesia Motor fluctuations Atypical parkinsonism Rigidity Bradykinesia Tremor, action NMS parkinsonism Parkinsonism Tremor (any or unspecified) Show more (+11) |
Behavioral abnormalities
Bradykinesia |
|
No
|
♀
|
C
|
NLD
|
18
|
n.a.
|
n.a.
|
Rigidity
Atypical parkinsonism Tremor (any or unspecified) Tremor, action Saccadic abnormalities Behavioral abnormalities Motor fluctuations Parkinsonism Postural instability Dyskinesia Gaze palsy Spasticity/pyramidal signs Bradykinesia Show more (+10) |
Tremor (any or unspecified)
Behavioral abnormalities |