Di Fonzo, 2009: Overview of all reported PARK-FBXO7 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
♂
|
C
|
ITA
|
13
|
n.a.
|
n.a.
|
Dyskinesia
Gaze palsy Dysphagia Tremor (any or unspecified) NMS parkinsonism Saccadic abnormalities Dystonia Tremor at rest Motor fluctuations Behavioral abnormalities Tremor, action Incontinence Parkinsonism Atypical parkinsonism Bradykinesia Rigidity Dysarthria/anarthria Postural instability Spasticity/pyramidal signs Show more (+16) |
Tremor (any or unspecified)
Rigidity |
|
Yes
|
♀
|
C
|
ITA
|
10
|
n.a.
|
n.a.
|
Bradykinesia
Tremor at rest Parkinsonism Dysphagia Tremor (any or unspecified) Dystonia Incontinence Micrographia Postural instability Rigidity NMS parkinsonism Atypical parkinsonism Dysarthria/anarthria Tremor, action Dyskinesia Spasticity/pyramidal signs Behavioral abnormalities Motor fluctuations Show more (+15) |
Tremor (any or unspecified)
Rigidity |
|
Yes
|
♂
|
C
|
NLD
|
19
|
n.a.
|
n.a.
|
NMS parkinsonism
Dysphagia Postural instability Behavioral abnormalities Tremor at rest Rigidity Atypical parkinsonism Dyskinesia Motor fluctuations Spasticity/pyramidal signs Tremor, action Tremor (any or unspecified) Bradykinesia Parkinsonism Show more (+11) |
Behavioral abnormalities
Bradykinesia |
|
No
|
♀
|
C
|
NLD
|
18
|
n.a.
|
n.a.
|
Dyskinesia
Saccadic abnormalities Tremor (any or unspecified) Postural instability Tremor, action Bradykinesia Motor fluctuations Gaze palsy Behavioral abnormalities Parkinsonism Spasticity/pyramidal signs Rigidity Atypical parkinsonism Show more (+10) |
Tremor (any or unspecified)
Behavioral abnormalities |