Paisán-Ruiz, 2010: Overview of all reported PARK-FBXO7 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♂
|
n.a.
|
TUR
|
17
|
n.a.
|
No
|
Bradykinesia
Hypomimia Postural instability Dysarthria/anarthria Oculogyric spasms Atypical parkinsonism NMS parkinsonism Parkinsonism Psychotic sign/sympt. Diurnal fluctuations Gait difficulties/falls Rigidity Dyskinesia Show more (+10) |
Gait difficulties/falls
|
|
No
|
♀
|
n.a.
|
PAK
|
22
|
22
|
n.a.
|
Psychotic sign/sympt.
Atypical parkinsonism Parkinsonism Postural instability Bradykinesia Cognitive decline Dystonia Dyskinesia Spasticity/pyramidal signs Show more (+6) |
Bradykinesia
|
|
No
|
♀
|
n.a.
|
PAK
|
24
|
44
|
n.a.
|
Postural instability
Respiratory sighs Cataracts Rigidity Dyskinesia Atypical parkinsonism Psychotic sign/sympt. Gaze palsy Parkinsonism Bradykinesia Spasticity/pyramidal signs Cognitive decline Show more (+9) |
Bradykinesia
|
|
Yes
|
♀
|
n.a.
|
PAK
|
17
|
22
|
n.a.
|
Respiratory sighs
Dyskinesia Atypical parkinsonism Spasticity/pyramidal signs Cataracts Dysarthria/anarthria Gaze palsy Postural instability Bradykinesia Psychotic sign/sympt. Rigidity Autonomic sign/sympt. Apraxia Cognitive decline Parkinsonism Show more (+12) |
Bradykinesia
Rigidity |