Paisán-Ruiz, 2010: Overview of all reported PARK-FBXO7 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♂
|
n.a.
|
TUR
|
17
|
n.a.
|
No
|
Gait difficulties/falls
Bradykinesia Postural instability Dysarthria/anarthria Dyskinesia Parkinsonism Hypomimia Rigidity Oculogyric spasms Atypical parkinsonism NMS parkinsonism Diurnal fluctuations Psychotic sign/sympt. Show more (+10) |
Gait difficulties/falls
|
|
No
|
♀
|
n.a.
|
PAK
|
22
|
22
|
n.a.
|
Spasticity/pyramidal signs
Parkinsonism Bradykinesia Cognitive decline Atypical parkinsonism Postural instability Dystonia Dyskinesia Psychotic sign/sympt. Show more (+6) |
Bradykinesia
|
|
No
|
♀
|
n.a.
|
PAK
|
24
|
44
|
n.a.
|
Bradykinesia
Gaze palsy Atypical parkinsonism Postural instability Cataracts Spasticity/pyramidal signs Rigidity Cognitive decline Parkinsonism Psychotic sign/sympt. Dyskinesia Respiratory sighs Show more (+9) |
Bradykinesia
|
|
Yes
|
♀
|
n.a.
|
PAK
|
17
|
22
|
n.a.
|
Parkinsonism
Respiratory sighs Rigidity Autonomic sign/sympt. Dyskinesia Postural instability Dysarthria/anarthria Spasticity/pyramidal signs Cataracts Apraxia Bradykinesia Gaze palsy Psychotic sign/sympt. Atypical parkinsonism Cognitive decline Show more (+12) |
Rigidity
Bradykinesia |