Paisán-Ruiz, 2010: Overview of all reported PARK-FBXO7 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♂
|
n.a.
|
TUR
|
17
|
n.a.
|
No
|
Diurnal fluctuations
Rigidity Dyskinesia Postural instability NMS parkinsonism Oculogyric spasms Bradykinesia Parkinsonism Dysarthria/anarthria Psychotic sign/sympt. Gait difficulties/falls Atypical parkinsonism Hypomimia Show more (+10) |
Gait difficulties/falls
|
|
No
|
♀
|
n.a.
|
PAK
|
22
|
22
|
n.a.
|
Cognitive decline
Dystonia Spasticity/pyramidal signs Atypical parkinsonism Parkinsonism Bradykinesia Psychotic sign/sympt. Dyskinesia Postural instability Show more (+6) |
Bradykinesia
|
|
No
|
♀
|
n.a.
|
PAK
|
24
|
44
|
n.a.
|
Rigidity
Respiratory sighs Parkinsonism Spasticity/pyramidal signs Postural instability Cataracts Dyskinesia Atypical parkinsonism Cognitive decline Psychotic sign/sympt. Bradykinesia Gaze palsy Show more (+9) |
Bradykinesia
|
|
Yes
|
♀
|
n.a.
|
PAK
|
17
|
22
|
n.a.
|
Gaze palsy
Spasticity/pyramidal signs Bradykinesia Postural instability Cognitive decline Apraxia Dyskinesia Autonomic sign/sympt. Psychotic sign/sympt. Rigidity Parkinsonism Dysarthria/anarthria Cataracts Atypical parkinsonism Respiratory sighs Show more (+12) |
Bradykinesia
Rigidity |