Paisán-Ruiz, 2010: Overview of all reported PARK-FBXO7 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♂
|
n.a.
|
TUR
|
17
|
n.a.
|
No
|
Bradykinesia
Hypomimia NMS parkinsonism Atypical parkinsonism Gait difficulties/falls Rigidity Parkinsonism Psychotic sign/sympt. Dysarthria/anarthria Oculogyric spasms Postural instability Dyskinesia Diurnal fluctuations Show more (+10) |
Gait difficulties/falls
|
|
No
|
♀
|
n.a.
|
PAK
|
22
|
22
|
n.a.
|
Postural instability
Bradykinesia Parkinsonism Cognitive decline Psychotic sign/sympt. Dyskinesia Dystonia Atypical parkinsonism Spasticity/pyramidal signs Show more (+6) |
Bradykinesia
|
|
No
|
♀
|
n.a.
|
PAK
|
24
|
44
|
n.a.
|
Psychotic sign/sympt.
Cognitive decline Respiratory sighs Dyskinesia Postural instability Atypical parkinsonism Gaze palsy Parkinsonism Rigidity Bradykinesia Cataracts Spasticity/pyramidal signs Show more (+9) |
Bradykinesia
|
|
Yes
|
♀
|
n.a.
|
PAK
|
17
|
22
|
n.a.
|
Psychotic sign/sympt.
Autonomic sign/sympt. Rigidity Dyskinesia Dysarthria/anarthria Gaze palsy Cognitive decline Parkinsonism Cataracts Respiratory sighs Spasticity/pyramidal signs Bradykinesia Postural instability Apraxia Atypical parkinsonism Show more (+12) |
Rigidity
Bradykinesia |