Paisán-Ruiz, 2010: Overview of all reported PARK-FBXO7 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♂
|
n.a.
|
TUR
|
17
|
n.a.
|
No
|
Rigidity
Dyskinesia Dysarthria/anarthria Hypomimia Psychotic sign/sympt. Bradykinesia Parkinsonism NMS parkinsonism Gait difficulties/falls Postural instability Atypical parkinsonism Diurnal fluctuations Oculogyric spasms Show more (+10) |
Gait difficulties/falls
|
|
No
|
♀
|
n.a.
|
PAK
|
22
|
22
|
n.a.
|
Dystonia
Parkinsonism Spasticity/pyramidal signs Atypical parkinsonism Dyskinesia Bradykinesia Cognitive decline Psychotic sign/sympt. Postural instability Show more (+6) |
Bradykinesia
|
|
No
|
♀
|
n.a.
|
PAK
|
24
|
44
|
n.a.
|
Spasticity/pyramidal signs
Atypical parkinsonism Parkinsonism Gaze palsy Bradykinesia Cognitive decline Cataracts Psychotic sign/sympt. Postural instability Rigidity Respiratory sighs Dyskinesia Show more (+9) |
Bradykinesia
|
|
Yes
|
♀
|
n.a.
|
PAK
|
17
|
22
|
n.a.
|
Spasticity/pyramidal signs
Bradykinesia Parkinsonism Rigidity Apraxia Psychotic sign/sympt. Autonomic sign/sympt. Dysarthria/anarthria Cataracts Gaze palsy Respiratory sighs Cognitive decline Atypical parkinsonism Postural instability Dyskinesia Show more (+12) |
Bradykinesia
Rigidity |