Paisán-Ruiz, 2010: Overview of all reported PARK-FBXO7 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♂
|
n.a.
|
TUR
|
17
|
n.a.
|
No
|
Hypomimia
Rigidity Oculogyric spasms Dysarthria/anarthria Gait difficulties/falls Bradykinesia Postural instability Dyskinesia Parkinsonism Atypical parkinsonism Diurnal fluctuations Psychotic sign/sympt. NMS parkinsonism Show more (+10) |
Gait difficulties/falls
|
|
No
|
♀
|
n.a.
|
PAK
|
22
|
22
|
n.a.
|
Bradykinesia
Atypical parkinsonism Dystonia Dyskinesia Spasticity/pyramidal signs Postural instability Parkinsonism Psychotic sign/sympt. Cognitive decline Show more (+6) |
Bradykinesia
|
|
No
|
♀
|
n.a.
|
PAK
|
24
|
44
|
n.a.
|
Psychotic sign/sympt.
Bradykinesia Dyskinesia Cognitive decline Rigidity Spasticity/pyramidal signs Atypical parkinsonism Parkinsonism Respiratory sighs Gaze palsy Cataracts Postural instability Show more (+9) |
Bradykinesia
|
|
Yes
|
♀
|
n.a.
|
PAK
|
17
|
22
|
n.a.
|
Atypical parkinsonism
Apraxia Respiratory sighs Gaze palsy Postural instability Dyskinesia Bradykinesia Autonomic sign/sympt. Rigidity Cataracts Parkinsonism Psychotic sign/sympt. Dysarthria/anarthria Cognitive decline Spasticity/pyramidal signs Show more (+12) |
Bradykinesia
Rigidity |