Tomiyama, 2006: Overview of all reported PARK-LRRK2 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♀
|
B
|
TUN
|
58
|
60
|
Yes
|
Parkinsonism
NMS parkinsonism Autonomic sign/sympt. Bradykinesia -Motor Sleep benefit Rigidity Tremor at rest Tremor (any or unspecified) Show more (+6) |
n.a.
|
|
Yes
|
♂
|
A
|
TWN
|
47
|
61
|
Yes
|
-Motor
Rigidity Tremor at rest Bradykinesia Tremor (any or unspecified) Parkinsonism Dyskinesia Show more (+4) |
n.a.
|
|
Yes
|
♀
|
A
|
n.a.
|
64
|
70
|
Yes
|
Rigidity
-Motor Psychotic sign/sympt. Postural instability Tremor at rest NMS parkinsonism Tremor (any or unspecified) Parkinsonism Bradykinesia Show more (+6) |
n.a.
|
|
Yes
|
♀
|
B
|
TUN
|
37
|
53
|
Yes
|
Bradykinesia
-Motor Tremor (any or unspecified) Rigidity Dyskinesia Tremor at rest Parkinsonism Show more (+4) |
n.a.
|
|
Yes
|
♂
|
C
|
ISR
|
60
|
78
|
Yes
|
Dyskinesia
Rigidity Postural instability -Motor Tremor (any or unspecified) Bradykinesia Parkinsonism Motor fluctuations Tremor at rest Show more (+6) |
n.a.
|
|
Yes
|
♀
|
C
|
ISR
|
41
|
50
|
No
|
Bradykinesia
Parkinsonism Postural instability -Motor Motor fluctuations Rigidity Dyskinesia Show more (+4) |
n.a.
|
|
Yes
|
♂
|
C
|
ISR
|
72
|
85
|
Yes
|
Bradykinesia
Rigidity Parkinsonism Dyskinesia Psychotic sign/sympt. NMS parkinsonism Tremor (any or unspecified) Motor fluctuations Postural instability Tremor at rest Cognitive decline -Motor Autonomic sign/sympt. Show more (+10) |
n.a.
|
|
Yes
|
♀
|
B
|
TUN
|
46
|
52
|
Yes
|
Tremor (any or unspecified)
Rigidity Tremor at rest Parkinsonism Psychotic sign/sympt. -Motor NMS parkinsonism Bradykinesia Show more (+5) |
n.a.
|
|
Yes
|
♀
|
C
|
ISR
|
66
|
74
|
Yes
|
-Motor
Rigidity Motor fluctuations Psychotic sign/sympt. Tremor (any or unspecified) Postural instability Cognitive decline Dyskinesia Depression Tremor at rest NMS parkinsonism Parkinsonism Bradykinesia Show more (+10) |
n.a.
|
|
Yes
|
♀
|
A
|
n.a.
|
53
|
61
|
Yes
|
-Motor
Motor fluctuations Rigidity Bradykinesia Parkinsonism Tremor at rest Tremor (any or unspecified) Show more (+4) |
n.a.
|