Mata, 2005: Overview of all reported PARK-LRRK2 patients

Index patient Sex Ethnicity Country of origin AAO AAE Family history Symptoms Initial symptoms Reported mutations
Yes
A
n.a.
58
n.a.
Yes
Cognitive decline
Postural instability
Bradykinesia
-Motor
Parkinsonism
Rigidity
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n.a.
Arg1441His: het
Yes
A
TWN
50
n.a.
Yes
Parkinsonism
-Motor
Rigidity
Postural instability
Bradykinesia
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n.a.
Gly2385Arg: het
Yes
C
n.a.
61
n.a.
Yes
Rigidity
Tremor at rest
Postural instability
-Motor
Parkinsonism
Bradykinesia
Tremor (any or unspecified)
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Bradykinesia
Tremor (any or unspecified)
Arg1441Gly: het
Yes
C
n.a.
40
n.a.
Yes
Tremor (any or unspecified)
Parkinsonism
-Motor
Tremor at rest
Rigidity
Bradykinesia
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Tremor (any or unspecified)
Gly2019Ser: het
Yes
C
n.a.
55
n.a.
Yes
Tremor at rest
Bradykinesia
Rigidity
-Motor
Tremor (any or unspecified)
Parkinsonism
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Bradykinesia
Arg1441Cys: het
Yes
C
NOR
70
n.a.
Yes
Parkinsonism
Bradykinesia
-Motor
Tremor at rest
Tremor (any or unspecified)
Rigidity
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n.a.
Met1869Thr: het