Zimprich, 2004: Overview of all reported PARK-LRRK2 patients

Index patient Sex Ethnicity Country of origin AAO AAE Family history Symptoms Initial symptoms Reported mutations
No
C
GBR
64
77
Yes
Rigidity
Motor fluctuations
Postural instability
Bradykinesia
Dyskinesia
Parkinsonism
Tremor at rest
Tremor (any or unspecified)
-Motor
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Tremor (any or unspecified)
Arg1441Cys: het
No
C
GBR
48
52
Yes
Bradykinesia
Rigidity
-Motor
Tremor at rest
Tremor (any or unspecified)
Parkinsonism
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Bradykinesia
Arg1441Cys: het
No
C
GBR
68
n.a.
Yes
Postural instability
-Motor
Parkinsonism
Tremor (any or unspecified)
Bradykinesia
Tremor at rest
Rigidity
Show more (+4)
Tremor (any or unspecified)
Arg1441Cys: het
No
C
GBR
78
89
Yes
-Motor
Postural instability
Tremor (any or unspecified)
Parkinsonism
Rigidity
Dystonia
Bradykinesia
Tremor at rest
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Bradykinesia
Arg1441Cys: het
No
C
GBR
49
65
Yes
Rigidity
Tremor (any or unspecified)
-Motor
Tremor at rest
Postural instability
Bradykinesia
Parkinsonism
Show more (+4)
Bradykinesia
Arg1441Cys: het
No
C
GBR
65
n.a.
Yes
Tremor at rest
Bradykinesia
Rigidity
Tremor (any or unspecified)
Parkinsonism
Postural instability
Dyskinesia
-Motor
Show more (+5)
Tremor (any or unspecified)
Arg1441Cys: het
No
C
GBR
58
89
Yes
Parkinsonism
Tremor (any or unspecified)
Bradykinesia
Cognitive decline
NMS parkinsonism
Tremor at rest
Postural instability
-Motor
Rigidity
Show more (+6)
Tremor (any or unspecified)
Bradykinesia
Arg1441Cys: het
Yes
C
GBR
57
65
Yes
-Motor
Dystonia
Postural instability
Tremor (any or unspecified)
Rigidity
Motor fluctuations
Bradykinesia
Dyskinesia
Parkinsonism
Show more (+6)
Bradykinesia
Arg1441Cys: het
No
C
GBR
70
82
Yes
Parkinsonism
Tremor (any or unspecified)
-Motor
Bradykinesia
Dyskinesia
Rigidity
Postural instability
Tremor at rest
Show more (+5)
Bradykinesia
Arg1441Cys: het