Abreu, 2016: Overview of all reported PARK-LRRK2 patients

Index patient Sex Ethnicity Country of origin AAO AAE Family history Symptoms Initial symptoms Reported mutations
Yes
H
BRA
41
49
Yes
Rigidity
Cognitive decline
Parkinsonism
Tremor at rest
Bradykinesia
-Motor
Postural instability
Tremor (any or unspecified)
Show more (+5)
Tremor (any or unspecified)
Gly2019Ser: het
Yes
H
n.a.
42
51
Yes
-Motor
Bradykinesia
Tremor at rest
Postural instability
Tremor (any or unspecified)
Parkinsonism
Rigidity
Show more (+4)
Tremor (any or unspecified)
Gly2019Ser: het
Yes
H
BRA
60
65
Yes
Postural instability
Rigidity
Bradykinesia
-Motor
Tremor at rest
Tremor (any or unspecified)
Parkinsonism
Show more (+4)
Tremor (any or unspecified)
Gly2019Ser: het
Yes
H
BRA
29
59
Yes
Postural instability
-Motor
Rigidity
Bradykinesia
Tremor (any or unspecified)
Tremor at rest
Parkinsonism
Show more (+4)
Tremor (any or unspecified)
Gly2019Ser: het
Yes
H
n.a.
47
64
Yes
Tremor (any or unspecified)
Tremor at rest
-Motor
Cognitive decline
Rigidity
Postural instability
Parkinsonism
Bradykinesia
Show more (+5)
Bradykinesia
Gly2019Ser: het
Yes
H
BRA
60
65
Yes
Cognitive decline
-Motor
Postural instability
Parkinsonism
Rigidity
Bradykinesia
Tremor (any or unspecified)
Tremor at rest
Show more (+5)
Tremor (any or unspecified)
Gly2019Ser: het