Heckman, 2016: Overview of all reported PARK-LRRK2 patients

Index patient Sex Ethnicity Country of origin AAO AAE Family history Symptoms Initial symptoms Reported mutations
No
C
USA
n.a.
76
No
-Motor
Parkinsonism
Rigidity
Tremor (any or unspecified)
Cognitive decline
Diurnal fluctuations
Sleep disorder
Bradykinesia
Tremor at rest
NMS parkinsonism
Psychotic sign/sympt.
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Tremor (any or unspecified)
Cognitive decline
Gly2019Ser: het