Heckman, 2016: Overview of all reported PARK-LRRK2 patients

Index patient Sex Ethnicity Country of origin AAO AAE Family history Symptoms Initial symptoms Reported mutations
No
C
USA
n.a.
76
No
-Motor
Diurnal fluctuations
NMS parkinsonism
Psychotic sign/sympt.
Bradykinesia
Cognitive decline
Rigidity
Tremor at rest
Parkinsonism
Tremor (any or unspecified)
Sleep disorder
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Cognitive decline
Tremor (any or unspecified)
Gly2019Ser: het