Hashad, 2011: Overview of all reported PARK-LRRK2 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♂
|
O
|
EGY
|
61
|
72
|
No
|
Cognitive decline
-Motor NMS parkinsonism Rigidity Postural instability Bradykinesia Tremor at rest Parkinsonism Psychotic sign/sympt. Tremor (any or unspecified) Show more (+7) |
Bradykinesia
Tremor at rest |
|
Yes
|
♀
|
O
|
EGY
|
60
|
67
|
No
|
Bradykinesia
Rigidity Tremor, action Tremor (any or unspecified) -Motor Postural instability Cognitive decline Psychotic sign/sympt. Tremor at rest Parkinsonism NMS parkinsonism Show more (+8) |
Bradykinesia
Rigidity |
|
Yes
|
♂
|
O
|
EGY
|
51
|
59
|
No
|
Cognitive decline
Parkinsonism NMS parkinsonism Rigidity Tremor (any or unspecified) Postural instability -Motor Bradykinesia Psychotic sign/sympt. Tremor at rest Show more (+7) |
Tremor at rest
|
|
Yes
|
♀
|
O
|
EGY
|
45
|
48
|
No
|
Parkinsonism
-Motor Tremor at rest Tremor, action Bradykinesia NMS parkinsonism Postural instability Psychotic sign/sympt. Rigidity Tremor (any or unspecified) Cognitive decline Depression Show more (+9) |
Tremor at rest
Postural instability |
|
Yes
|
♀
|
O
|
EGY
|
61
|
63
|
No
|
-Motor
NMS parkinsonism Psychotic sign/sympt. Cognitive decline Parkinsonism Tremor at rest Bradykinesia Rigidity Tremor (any or unspecified) Show more (+6) |
Tremor at rest
Bradykinesia |
|
Yes
|
♀
|
O
|
EGY
|
62
|
70
|
No
|
NMS parkinsonism
Tremor, action -Motor Depression Parkinsonism Tremor at rest Postural instability Rigidity Psychotic sign/sympt. Cognitive decline Tremor (any or unspecified) Bradykinesia Show more (+9) |
Tremor at rest
|
|
Yes
|
♂
|
O
|
EGY
|
53
|
62
|
No
|
Parkinsonism
Postural instability Rigidity Tremor at rest -Motor Cognitive decline Tremor (any or unspecified) Bradykinesia Show more (+5) |
Rigidity
Tremor at rest Bradykinesia |
|
Yes
|
♂
|
O
|
EGY
|
55
|
58
|
No
|
NMS parkinsonism
Tremor (any or unspecified) Psychotic sign/sympt. Tremor, action Postural instability -Motor Rigidity Cognitive decline Tremor at rest Depression Bradykinesia Parkinsonism Show more (+9) |
Rigidity
Tremor at rest Bradykinesia |
|
Yes
|
♂
|
O
|
EGY
|
49
|
53
|
No
|
Parkinsonism
Tremor (any or unspecified) Bradykinesia Tremor at rest Psychotic sign/sympt. -Motor NMS parkinsonism Rigidity Cognitive decline Show more (+6) |
Tremor at rest
|
|
Yes
|
♂
|
O
|
EGY
|
55
|
58
|
No
|
Bradykinesia
Rigidity Parkinsonism -Motor NMS parkinsonism Tremor, action Psychotic sign/sympt. Cognitive decline Depression Postural instability Tremor (any or unspecified) Tremor at rest Show more (+9) |
Bradykinesia
Rigidity |