Papapetropoulos, 2006: Overview of all reported PARK-LRRK2 patients

Index patient Sex Ethnicity Country of origin AAO AAE Family history Symptoms Initial symptoms Reported mutations
Yes
C
n.a.
77
81
No
-Motor
Depression
NMS parkinsonism
Tremor (any or unspecified)
Parkinsonism
Tremor at rest
Cognitive decline
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Tremor at rest
Gly2019Ser: het
Yes
C
n.a.
41
70
No
Parkinsonism
Dyskinesia
Motor fluctuations
Cognitive decline
Psychotic sign/sympt.
Tremor (any or unspecified)
Depression
-Motor
Tremor at rest
Postural instability
Autonomic sign/sympt.
NMS parkinsonism
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Tremor at rest
Gly2019Ser: het
Yes
C
n.a.
50
65
Yes
-Motor
Rigidity
Tremor at rest
Parkinsonism
Dyskinesia
Motor fluctuations
Tremor (any or unspecified)
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Rigidity
Tremor at rest
Gly2019Ser: het
Yes
C
n.a.
79
n.a.
No
Cognitive decline
Parkinsonism
Tremor, action
-Motor
Bradykinesia
Tremor (any or unspecified)
NMS parkinsonism
Rigidity
Depression
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n.a.
Gly2019Ser: het