Goldwurm, 2006: Overview of all reported PARK-LRRK2 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♀
|
C
|
ITA
|
53
|
56
|
No
|
Postural instability
Bradykinesia Rigidity Anxiety NMS parkinsonism Sleep benefit Sleep disorder Dystonia Depression Tremor (any or unspecified) Tremor at rest Parkinsonism -Motor Show more (+10) |
Bradykinesia
Tremor (any or unspecified) |
|
Yes
|
♀
|
C
|
ITA
|
51
|
62
|
No
|
Bradykinesia
Cognitive decline -Motor NMS parkinsonism Postural instability Dystonia Psychotic sign/sympt. Motor fluctuations Anxiety Depression Parkinsonism Dyskinesia Sleep benefit Rigidity Sleep disorder Show more (+12) |
Depression
Rigidity |
|
Yes
|
♂
|
C
|
ITA
|
53
|
69
|
Yes
|
Dystonia
Motor fluctuations Bradykinesia Psychotic sign/sympt. NMS parkinsonism Parkinsonism Anxiety Dyskinesia Rigidity -Motor Depression Sleep disorder Postural instability Show more (+10) |
Bradykinesia
|
|
Yes
|
♀
|
C
|
ITA
|
63
|
72
|
No
|
Depression
NMS parkinsonism Tremor at rest Bradykinesia Motor fluctuations -Motor Dyskinesia Cognitive decline Parkinsonism Dystonia Postural instability Psychotic sign/sympt. Tremor (any or unspecified) Rigidity Show more (+11) |
Bradykinesia
Tremor (any or unspecified) |
|
Yes
|
♂
|
C
|
ITA
|
40
|
43
|
No
|
Sleep disorder
Depression Bradykinesia NMS parkinsonism Tremor at rest Parkinsonism Dystonia -Motor Motor fluctuations Tremor (any or unspecified) Rigidity Show more (+8) |
Bradykinesia
Tremor (any or unspecified) Rigidity |
|
Yes
|
♀
|
C
|
ITA
|
68
|
75
|
No
|
-Motor
Postural instability Bradykinesia Anxiety Motor fluctuations Sleep disorder Rigidity Cognitive decline Parkinsonism Sleep benefit Dyskinesia NMS parkinsonism Depression Show more (+10) |
Bradykinesia
Depression |