Marongiu, 2006: Overview of all reported PARK-LRRK2 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♂
|
n.a.
|
ITA
|
40
|
41
|
No
|
Tremor at rest
Tremor (any or unspecified) Parkinsonism -Motor Bradykinesia Anxiety NMS parkinsonism Rigidity Show more (+5) |
Rigidity
|
|
Yes
|
♀
|
n.a.
|
ITA
|
78
|
81
|
Yes
|
Tremor at rest
Tremor (any or unspecified) Dyskinesia Cognitive decline Bradykinesia -Motor Rigidity Parkinsonism Show more (+5) |
Tremor (any or unspecified)
|
|
Yes
|
♂
|
n.a.
|
ITA
|
58
|
69
|
No
|
Rigidity
|
||
Yes
|
♀
|
n.a.
|
ITA
|
55
|
75
|
Yes
|
Rigidity
Dyskinesia Parkinsonism -Motor Motor fluctuations Bradykinesia NMS parkinsonism Show more (+4) |
Rigidity
|
|
Yes
|
♂
|
n.a.
|
ITA
|
58
|
78
|
No
|
Motor fluctuations
-Motor Parkinsonism Rigidity Tremor (any or unspecified) Dyskinesia Bradykinesia Tremor at rest Show more (+5) |
Tremor (any or unspecified)
|
|
Yes
|
♀
|
n.a.
|
ITA
|
57
|
65
|
Yes
|
Autonomic sign/sympt.
Bradykinesia Tremor (any or unspecified) -Motor Tremor at rest Motor fluctuations Parkinsonism Dyskinesia NMS parkinsonism Rigidity Show more (+7) |
Rigidity
|
|
Yes
|
♀
|
n.a.
|
ITA
|
54
|
60
|
Yes
|
NMS parkinsonism
Depression -Motor Autonomic sign/sympt. Tremor (any or unspecified) Tremor at rest Rigidity Parkinsonism Show more (+5) |
Tremor (any or unspecified)
|
|
Yes
|
♂
|
n.a.
|
ITA
|
35
|
40
|
No
|
Bradykinesia
|
||
Yes
|
♂
|
n.a.
|
ITA
|
39
|
44
|
No
|
Anxiety
Dyskinesia Hyperreflexia Bradykinesia -Motor Parkinsonism Rigidity Tremor at rest Tremor (any or unspecified) NMS parkinsonism Show more (+7) |
Tremor (any or unspecified)
|
|
Yes
|
♀
|
n.a.
|
ITA
|
47
|
60
|
No
|
-Motor
Parkinsonism Bradykinesia Tremor at rest Depression Tremor (any or unspecified) Rigidity NMS parkinsonism Show more (+5) |
Tremor (any or unspecified)
|