Marongiu, 2006: Overview of all reported PARK-LRRK2 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♂
|
n.a.
|
ITA
|
40
|
41
|
No
|
Parkinsonism
-Motor Tremor (any or unspecified) Anxiety NMS parkinsonism Rigidity Tremor at rest Bradykinesia Show more (+5) |
Rigidity
|
|
Yes
|
♀
|
n.a.
|
ITA
|
78
|
81
|
Yes
|
Bradykinesia
Rigidity Parkinsonism Tremor at rest Cognitive decline Dyskinesia Tremor (any or unspecified) -Motor Show more (+5) |
Tremor (any or unspecified)
|
|
Yes
|
♂
|
n.a.
|
ITA
|
58
|
69
|
No
|
Rigidity
|
||
Yes
|
♀
|
n.a.
|
ITA
|
55
|
75
|
Yes
|
-Motor
Bradykinesia Dyskinesia Rigidity Motor fluctuations NMS parkinsonism Parkinsonism Show more (+4) |
Rigidity
|
|
Yes
|
♂
|
n.a.
|
ITA
|
58
|
78
|
No
|
Motor fluctuations
Bradykinesia Parkinsonism Rigidity Tremor (any or unspecified) -Motor Tremor at rest Dyskinesia Show more (+5) |
Tremor (any or unspecified)
|
|
Yes
|
♀
|
n.a.
|
ITA
|
57
|
65
|
Yes
|
Tremor (any or unspecified)
Motor fluctuations Rigidity -Motor Dyskinesia NMS parkinsonism Bradykinesia Tremor at rest Autonomic sign/sympt. Parkinsonism Show more (+7) |
Rigidity
|
|
Yes
|
♀
|
n.a.
|
ITA
|
54
|
60
|
Yes
|
Rigidity
Tremor (any or unspecified) Parkinsonism Depression Tremor at rest -Motor NMS parkinsonism Autonomic sign/sympt. Show more (+5) |
Tremor (any or unspecified)
|
|
Yes
|
♂
|
n.a.
|
ITA
|
35
|
40
|
No
|
Bradykinesia
|
||
Yes
|
♂
|
n.a.
|
ITA
|
39
|
44
|
No
|
Tremor (any or unspecified)
Hyperreflexia -Motor NMS parkinsonism Anxiety Bradykinesia Rigidity Tremor at rest Dyskinesia Parkinsonism Show more (+7) |
Tremor (any or unspecified)
|
|
Yes
|
♀
|
n.a.
|
ITA
|
47
|
60
|
No
|
Tremor (any or unspecified)
Bradykinesia NMS parkinsonism Tremor at rest Parkinsonism Rigidity -Motor Depression Show more (+5) |
Tremor (any or unspecified)
|