Marongiu, 2006: Overview of all reported PARK-LRRK2 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♂
|
n.a.
|
ITA
|
40
|
41
|
No
|
-Motor
Tremor at rest Bradykinesia Parkinsonism NMS parkinsonism Anxiety Tremor (any or unspecified) Rigidity Show more (+5) |
Rigidity
|
|
Yes
|
♀
|
n.a.
|
ITA
|
78
|
81
|
Yes
|
Tremor at rest
Bradykinesia -Motor Dyskinesia Tremor (any or unspecified) Rigidity Cognitive decline Parkinsonism Show more (+5) |
Tremor (any or unspecified)
|
|
Yes
|
♂
|
n.a.
|
ITA
|
58
|
69
|
No
|
Rigidity
|
||
Yes
|
♀
|
n.a.
|
ITA
|
55
|
75
|
Yes
|
Dyskinesia
Bradykinesia Rigidity NMS parkinsonism Motor fluctuations -Motor Parkinsonism Show more (+4) |
Rigidity
|
|
Yes
|
♂
|
n.a.
|
ITA
|
58
|
78
|
No
|
Motor fluctuations
Bradykinesia Dyskinesia Parkinsonism Tremor at rest Rigidity -Motor Tremor (any or unspecified) Show more (+5) |
Tremor (any or unspecified)
|
|
Yes
|
♀
|
n.a.
|
ITA
|
57
|
65
|
Yes
|
Tremor (any or unspecified)
-Motor Tremor at rest Dyskinesia Bradykinesia NMS parkinsonism Motor fluctuations Rigidity Autonomic sign/sympt. Parkinsonism Show more (+7) |
Rigidity
|
|
Yes
|
♀
|
n.a.
|
ITA
|
54
|
60
|
Yes
|
Depression
Rigidity NMS parkinsonism Tremor at rest Tremor (any or unspecified) -Motor Autonomic sign/sympt. Parkinsonism Show more (+5) |
Tremor (any or unspecified)
|
|
Yes
|
♂
|
n.a.
|
ITA
|
35
|
40
|
No
|
Bradykinesia
|
||
Yes
|
♂
|
n.a.
|
ITA
|
39
|
44
|
No
|
Tremor at rest
Dyskinesia NMS parkinsonism -Motor Hyperreflexia Parkinsonism Anxiety Bradykinesia Rigidity Tremor (any or unspecified) Show more (+7) |
Tremor (any or unspecified)
|
|
Yes
|
♀
|
n.a.
|
ITA
|
47
|
60
|
No
|
-Motor
Tremor at rest NMS parkinsonism Bradykinesia Parkinsonism Rigidity Tremor (any or unspecified) Depression Show more (+5) |
Tremor (any or unspecified)
|