Khan, 2005: Overview of all reported PARK-LRRK2 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♂
|
C
|
GBR
|
56
|
70
|
Yes
|
Tremor (any or unspecified)
-Motor Tremor at rest Dyskinesia NMS parkinsonism Dystonia Anxiety Olfactory impairment Parkinsonism Show more (+6) |
Tremor (any or unspecified)
Anxiety |
|
Yes
|
♂
|
C
|
GBR
|
44
|
47
|
Yes
|
Tremor (any or unspecified)
|
||
Yes
|
♀
|
C
|
GBR
|
67
|
81
|
Yes
|
Tremor at rest
Bradykinesia Tremor (any or unspecified) Dyskinesia -Motor Parkinsonism Rigidity Show more (+4) |
Bradykinesia
Tremor (any or unspecified) |
|
Yes
|
♂
|
C
|
GBR
|
59
|
61
|
Yes
|
Bradykinesia
|
||
Yes
|
♂
|
C
|
GBR
|
45
|
70
|
Yes
|
-Motor
Bradykinesia Depression Dystonia NMS parkinsonism Rigidity Olfactory impairment Parkinsonism Tremor (any or unspecified) Show more (+6) |
Tremor (any or unspecified)
|
|
Yes
|
♀
|
C
|
GBR
|
45
|
57
|
Yes
|
Depression
Dyskinesia Parkinsonism -Motor NMS parkinsonism Psychotic sign/sympt. Tremor at rest Dystonia Rigidity Anxiety Autonomic sign/sympt. Tremor (any or unspecified) Show more (+9) |
Rigidity
Tremor (any or unspecified) |
|
Yes
|
♂
|
C
|
GBR
|
40
|
49
|
Yes
|
Tremor (any or unspecified)
|
||
Yes
|
♀
|
C
|
GBR
|
57
|
77
|
Yes
|
Bradykinesia
Motor fluctuations -Motor Tremor (any or unspecified) Parkinsonism Atypical parkinsonism Show more (+3) |
n.a.
|
|
Yes
|
♂
|
C
|
GBR
|
50
|
70
|
Yes
|
n.a.
|
||
Yes
|
♂
|
C
|
GBR
|
50
|
54
|
Yes
|
n.a.
|