Floris, 2009: Overview of all reported PARK-LRRK2 patients

Index patient Sex Ethnicity Country of origin AAO AAE Family history Symptoms Initial symptoms Reported mutations
Yes
n.a.
ITA
69
75
Yes
Tremor (any or unspecified)
-Motor
NMS parkinsonism
Parkinsonism
Anxiety
Show more (+2)
Tremor (any or unspecified)
Gly2019Ser: het
Yes
n.a.
ITA
65
78
n.a.
Parkinsonism
Anxiety
-Motor
NMS parkinsonism
Tremor (any or unspecified)
Show more (+2)
Tremor (any or unspecified)
Gly2019Ser: het
Yes
n.a.
ITA
67
69
n.a.
Anxiety
Parkinsonism
-Motor
Tremor (any or unspecified)
NMS parkinsonism
Show more (+2)
Tremor (any or unspecified)
Gly2019Ser: het
Yes
n.a.
ITA
62
73
n.a.
Parkinsonism
Tremor (any or unspecified)
Motor fluctuations
Dyskinesia
Depression
NMS parkinsonism
-Motor
Anxiety
Show more (+5)
Tremor (any or unspecified)
Gly2019Ser: het
Yes
n.a.
ITA
44
56
n.a.
NMS parkinsonism
Dystonia
Depression
Anxiety
Tremor (any or unspecified)
-Motor
Rigidity
Parkinsonism
Show more (+5)
Tremor (any or unspecified)
Rigidity
Gly2019Ser: het
Yes
n.a.
ITA
77
83
n.a.
-Motor
Rigidity
Parkinsonism
Rigidity
Gly2019Ser: het
Yes
n.a.
ITA
60
68
n.a.
Parkinsonism
Tremor (any or unspecified)
NMS parkinsonism
Anxiety
Rigidity
-Motor
Depression
Show more (+4)
Tremor (any or unspecified)
Arg1441Cys: het
Yes
n.a.
ITA
78
79
Yes
Parkinsonism
Tremor (any or unspecified)
-Motor
Tremor (any or unspecified)
Gly2019Ser: het
Yes
n.a.
ITA
59
69
n.a.
Dystonia
Depression
Tremor (any or unspecified)
Cognitive decline
Anxiety
NMS parkinsonism
Motor fluctuations
-Motor
Dyskinesia
Rigidity
Parkinsonism
Show more (+8)
Tremor (any or unspecified)
Arg1441Cys: het