Ferreira, 2007: Overview of all reported PARK-LRRK2 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♂
|
C
|
PRT
|
56
|
67
|
No
|
Bradykinesia
Rigidity |
||
Yes
|
♀
|
C
|
PRT
|
61
|
63
|
Yes
|
-Motor
Olfactory impairment Bradykinesia Autonomic sign/sympt. NMS parkinsonism Tremor (any or unspecified) Parkinsonism Sleep disorder Show more (+5) |
Bradykinesia
Tremor (any or unspecified) |
|
Yes
|
♀
|
C
|
PRT
|
32
|
56
|
Yes
|
Motor fluctuations
Rigidity Autonomic sign/sympt. Sleep disorder Olfactory impairment Bradykinesia Parkinsonism -Motor Dyskinesia NMS parkinsonism Show more (+7) |
Rigidity
Bradykinesia |
|
Yes
|
♂
|
C
|
PRT
|
56
|
60
|
No
|
Bradykinesia
NMS parkinsonism Parkinsonism Psychotic sign/sympt. Sleep disorder Tremor (any or unspecified) Autonomic sign/sympt. Depression -Motor Anxiety Olfactory impairment Show more (+8) |
Bradykinesia
Tremor (any or unspecified) |
|
No
|
♀
|
C
|
PRT
|
72
|
80
|
Yes
|
-Motor
Olfactory impairment Parkinsonism Bradykinesia Sleep disorder NMS parkinsonism Depression Show more (+4) |
Bradykinesia
|
|
Yes
|
♀
|
C
|
PRT
|
24
|
48
|
No
|
Olfactory impairment
NMS parkinsonism Depression Autonomic sign/sympt. Parkinsonism Sleep disorder Tremor (any or unspecified) -Motor Show more (+5) |
Tremor (any or unspecified)
|
|
Yes
|
♀
|
C
|
PRT
|
57
|
60
|
Yes
|
Tremor (any or unspecified)
-Motor Depression Olfactory impairment Parkinsonism Sleep disorder NMS parkinsonism Bradykinesia Show more (+5) |
Tremor (any or unspecified)
Bradykinesia |
|
Yes
|
♂
|
C
|
PRT
|
47
|
71
|
Yes
|
Autonomic sign/sympt.
Sleep disorder Olfactory impairment -Motor Parkinsonism NMS parkinsonism Depression Bradykinesia Show more (+5) |
Bradykinesia
|
|
Yes
|
♀
|
C
|
PRT
|
57
|
69
|
No
|
Autonomic sign/sympt.
-Motor Depression Tremor (any or unspecified) Parkinsonism Olfactory impairment NMS parkinsonism Sleep disorder Show more (+5) |
Tremor (any or unspecified)
|
|
No
|
♂
|
C
|
PRT
|
57
|
81
|
Yes
|
Bradykinesia
Psychotic sign/sympt. Dyskinesia Rigidity NMS parkinsonism Olfactory impairment Motor fluctuations -Motor Parkinsonism Show more (+6) |
Bradykinesia
Rigidity |