Ruffmann, 2012: Overview of all reported PARK-LRRK2 patients

Index patient Sex Ethnicity Country of origin AAO AAE Family history Symptoms Initial symptoms Reported mutations
Yes
n.a.
n.a.
72
n.a.
n.a.
Tremor (any or unspecified)
Cognitive decline
NMS parkinsonism
Depression
Bradykinesia
Tremor at rest
-Motor
Parkinsonism
Postural instability
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Tremor at rest
Gly2019Ser: het