Di Fonzo, 2005: Overview of all reported PARK-LRRK2 patients

Index patient Sex Ethnicity Country of origin AAO AAE Family history Symptoms Initial symptoms Reported mutations
No
n.a.
n.a.
PRT
68
69
Yes
NMS parkinsonism
Tremor (any or unspecified)
-Motor
Sleep disorder
Bradykinesia
Parkinsonism
Tremor at rest
Rigidity
Show more (+5)
n.a.
Gly2019Ser: het
Yes
n.a.
n.a.
ITA
50
66
Yes
Parkinsonism
Motor fluctuations
Rigidity
Dyskinesia
Tremor at rest
Tremor (any or unspecified)
-Motor
Bradykinesia
Dystonia
Show more (+6)
n.a.
Gly2019Ser: het
No
n.a.
n.a.
ITA
n.a.
n.a.
Yes
Parkinsonism
-Motor
n.a.
Gly2019Ser: het
No
n.a.
n.a.
PRT
61
64
Yes
Bradykinesia
Parkinsonism
Sleep disorder
Dystonia
-Motor
NMS parkinsonism
Rigidity
Tremor at rest
Tremor (any or unspecified)
Show more (+6)
n.a.
Gly2019Ser: het
No
n.a.
n.a.
ITA
38
43
Yes
Parkinsonism
-Motor
Bradykinesia
Rigidity
Show more (+1)
n.a.
Gly2019Ser: het
No
n.a.
n.a.
ITA
55
61
Yes
Tremor (any or unspecified)
Rigidity
Motor fluctuations
-Motor
Bradykinesia
Dyskinesia
Tremor at rest
Parkinsonism
Show more (+5)
n.a.
Gly2019Ser: het
Yes
n.a.
n.a.
ITA
38
46
Yes
Dystonia
-Motor
Motor fluctuations
Parkinsonism
Dyskinesia
Rigidity
Bradykinesia
Show more (+4)
n.a.
Gly2019Ser: het
Yes
n.a.
n.a.
BRA
46
61
Yes
Bradykinesia
Dyskinesia
Parkinsonism
-Motor
Rigidity
Motor fluctuations
Tremor (any or unspecified)
Tremor at rest
Show more (+5)
n.a.
Gly2019Ser: het
Yes
n.a.
n.a.
PRT
67
72
Yes
-Motor
Parkinsonism
Bradykinesia
NMS parkinsonism
Autonomic sign/sympt.
Sleep disorder
Tremor (any or unspecified)
Dystonia
Tremor at rest
Show more (+6)
n.a.
Gly2019Ser: het