Di Fonzo, 2005: Overview of all reported PARK-LRRK2 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
n.a.
|
n.a.
|
PRT
|
68
|
69
|
Yes
|
Bradykinesia
Tremor (any or unspecified) Parkinsonism Sleep disorder Tremor at rest -Motor NMS parkinsonism Rigidity Show more (+5) |
n.a.
|
|
Yes
|
n.a.
|
n.a.
|
ITA
|
50
|
66
|
Yes
|
Motor fluctuations
Tremor (any or unspecified) Dyskinesia Rigidity Dystonia Tremor at rest Bradykinesia Parkinsonism -Motor Show more (+6) |
n.a.
|
|
No
|
n.a.
|
n.a.
|
ITA
|
n.a.
|
n.a.
|
Yes
|
Parkinsonism
-Motor |
n.a.
|
|
No
|
n.a.
|
n.a.
|
PRT
|
61
|
64
|
Yes
|
Bradykinesia
Rigidity -Motor Tremor (any or unspecified) Dystonia Sleep disorder Tremor at rest NMS parkinsonism Parkinsonism Show more (+6) |
n.a.
|
|
No
|
n.a.
|
n.a.
|
ITA
|
38
|
43
|
Yes
|
n.a.
|
||
No
|
n.a.
|
n.a.
|
ITA
|
55
|
61
|
Yes
|
Bradykinesia
Rigidity Motor fluctuations Tremor at rest -Motor Dyskinesia Parkinsonism Tremor (any or unspecified) Show more (+5) |
n.a.
|
|
Yes
|
n.a.
|
n.a.
|
ITA
|
38
|
46
|
Yes
|
n.a.
|
||
Yes
|
n.a.
|
n.a.
|
BRA
|
46
|
61
|
Yes
|
Motor fluctuations
Bradykinesia Tremor at rest Rigidity Tremor (any or unspecified) -Motor Dyskinesia Parkinsonism Show more (+5) |
n.a.
|
|
Yes
|
n.a.
|
n.a.
|
PRT
|
67
|
72
|
Yes
|
Bradykinesia
Dystonia Autonomic sign/sympt. Tremor at rest Sleep disorder NMS parkinsonism Tremor (any or unspecified) Parkinsonism -Motor Show more (+6) |
n.a.
|