Zühlke, 2001: Overview of all reported ATX-TBP patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♂
|
C
|
DEU
|
n.a.
|
21
|
n.a.
|
Mental deterioration
Atrophy/degeneration affecting the brainstem Gait ataxia Ataxia, limb Rigidity Ataxia Dysarthria Postural tremor, upper limb Tremor (any or unspecified) Nystagmus Cerebellar atrophy Autonomic dysfunction Dysmetric saccades Tremor, kinetic Show more (+11) |
Mental deterioration
Gait ataxia Dysarthria |
|
Yes
|
n.a.
|
C
|
DEU
|
n.a.
|
n.a.
|
n.a.
|
Ataxia
|
n.a.
|
|
No
|
♀
|
C
|
DEU
|
20
|
23
|
n.a.
|
Head titubation
Dystonia, limb Ataxia Ataxia, limb Dysarthria Dystonia, cervical Rigidity Dystonia (any or unspecified) Show more (+5) |
Dystonia, limb
|
|
Yes
|
♀
|
C
|
DEU
|
34
|
47
|
n.a.
|
Cerebral atrophy
Parkinsonism Dystonia, limb Ataxia Postural instability Behavioural abnormality Dysmetric saccades Bradykinesia Rigidity Dystonia (any or unspecified) Cerebellar atrophy Mental deterioration Spasticity Autonomic dysfunction Dysarthria Show more (+12) |
Dystonia, limb
Ataxia Behavioural abnormality |
|
No
|
♀
|
C
|
DEU
|
n.a.
|
49
|
n.a.
|
Ataxia
|
n.a.
|