Bruni, 2004: Overview of all reported ATX-TBP patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
♂
|
n.a.
|
ITA
|
22
|
51
|
n.a.
|
Motor fluctuations
Behavioural abnormality Cerebral atrophy Dysarthria Rigidity Dystonia (any or unspecified) Mental deterioration Autonomic dysfunction Psychosis Ataxia Cerebellar atrophy Show more (+8) |
Behavioural abnormality
|
|
No
|
♀
|
n.a.
|
ITA
|
33
|
63
|
n.a.
|
Rigidity
Dystonia (any or unspecified) Autonomic dysfunction Anxiety Cerebellar atrophy Mental deterioration Psychosis Apathy Ataxia Dysarthria Behavioural abnormality Cerebral atrophy Show more (+9) |
Behavioural abnormality
|
|
No
|
♂
|
n.a.
|
ITA
|
20
|
60
|
n.a.
|
Apathy
Dystonia (any or unspecified) Rigidity Dysarthria Mental deterioration Behavioural abnormality Seizures Ataxia Autonomic dysfunction Psychosis Show more (+7) |
n.a.
|
|
No
|
♀
|
n.a.
|
ITA
|
35
|
44
|
n.a.
|
Apathy
Anxiety Ataxia Psychosis Mental deterioration Dysarthria Dystonia (any or unspecified) Behavioural abnormality Cerebral atrophy Rigidity Depression Cerebellar atrophy Show more (+9) |
Behavioural abnormality
|
|
No
|
♀
|
n.a.
|
ITA
|
33
|
42
|
n.a.
|
Autonomic dysfunction
Ataxia Cerebellar atrophy Behavioural abnormality Rigidity Dystonia (any or unspecified) Cerebral atrophy Mental deterioration Dysarthria Show more (+6) |
Behavioural abnormality
|
|
No
|
♀
|
n.a.
|
ITA
|
53
|
65
|
n.a.
|
Rigidity
Mental deterioration Autonomic dysfunction Behavioural abnormality Dysarthria Ataxia Show more (+3) |
Behavioural abnormality
|
|
Yes
|
♀
|
n.a.
|
ITA
|
26
|
40
|
n.a.
|
Dysarthria
Wheelchair Walking aids Dystonia, limb Dystonia (any or unspecified) Behavioural abnormality Apathy Autonomic dysfunction Mutism Tremor (any or unspecified) Ataxia Dysphagia Seizures Gait ataxia Cerebral atrophy Cerebellar atrophy Rigidity Depression Slow saccades Myoclonus Muscle atrophy Muscle weakness Mental deterioration Show more (+20) |
Behavioural abnormality
Apathy Gait ataxia |