Bruni, 2004: Overview of all reported ATX-TBP patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
♂
|
n.a.
|
ITA
|
22
|
51
|
n.a.
|
Motor fluctuations
Autonomic dysfunction Behavioural abnormality Dystonia (any or unspecified) Mental deterioration Ataxia Dysarthria Rigidity Cerebral atrophy Psychosis Cerebellar atrophy Show more (+8) |
Behavioural abnormality
|
|
No
|
♀
|
n.a.
|
ITA
|
33
|
63
|
n.a.
|
Autonomic dysfunction
Cerebellar atrophy Ataxia Rigidity Psychosis Dysarthria Behavioural abnormality Apathy Cerebral atrophy Anxiety Mental deterioration Dystonia (any or unspecified) Show more (+9) |
Behavioural abnormality
|
|
No
|
♂
|
n.a.
|
ITA
|
20
|
60
|
n.a.
|
Ataxia
Autonomic dysfunction Psychosis Seizures Apathy Dysarthria Rigidity Mental deterioration Dystonia (any or unspecified) Behavioural abnormality Show more (+7) |
n.a.
|
|
No
|
♀
|
n.a.
|
ITA
|
35
|
44
|
n.a.
|
Anxiety
Dysarthria Psychosis Mental deterioration Dystonia (any or unspecified) Rigidity Apathy Ataxia Cerebral atrophy Behavioural abnormality Depression Cerebellar atrophy Show more (+9) |
Behavioural abnormality
|
|
No
|
♀
|
n.a.
|
ITA
|
33
|
42
|
n.a.
|
Dystonia (any or unspecified)
Cerebellar atrophy Behavioural abnormality Dysarthria Ataxia Cerebral atrophy Mental deterioration Rigidity Autonomic dysfunction Show more (+6) |
Behavioural abnormality
|
|
No
|
♀
|
n.a.
|
ITA
|
53
|
65
|
n.a.
|
Ataxia
Behavioural abnormality Mental deterioration Autonomic dysfunction Dysarthria Rigidity Show more (+3) |
Behavioural abnormality
|
|
Yes
|
♀
|
n.a.
|
ITA
|
26
|
40
|
n.a.
|
Dysphagia
Rigidity Dysarthria Dystonia (any or unspecified) Depression Seizures Dystonia, limb Muscle atrophy Cerebral atrophy Ataxia Tremor (any or unspecified) Gait ataxia Walking aids Behavioural abnormality Muscle weakness Slow saccades Autonomic dysfunction Apathy Myoclonus Cerebellar atrophy Mutism Mental deterioration Wheelchair Show more (+20) |
Gait ataxia
Behavioural abnormality Apathy |