Overview of included studies for PARK-PRKN:
Filter for
carrying
Country
Study Study design N cases Ethnicities Sex
(% ♂) 		Mean AAO (+/- SD) Reported mutations
Clark, 2006 Mutational screen 1 C n.a. 38 p.Pro113Thrfs*51: hom
Nakaso, 2006 Family study 2 A 50% 49(+/-4) c.(171+1_172-1)_(618+1_619-1)del: hom
c.(171+1_172-1)_(534+1_535-1)del: hom
De Rosa, 2006 Other/Mixed 4 n.a. 75% 32(+/-12) c.(7+1_8-1)_(534+1_535-1)del
+ c.(7+1_8-1)_(171+1_172-1)del: comp. het.
c.(171+1_172-1)_(412+1_413-1)del: hom
c.(171+1_172-1)_(412+1_413-1)del
+ c.(7+1_8-1)_(412+1_413-1)del: comp. het.
c.(171+1_172-1)_(534+1_535-1)del: hom
 Show more (+1)
Deng, 2006 Other/Mixed 4 n.a. 50% 35(+/-3) c.(534+1_535-1)_(734+1_735-1)del
+ p.Thr240Met: comp. het.
Madegowda, 2005 Mutational screen 2 I 0% 39(+/-8) c.(871+1_872-1)_(1083+1_1084-1)del: hom
Ohsawa, 2005 Other/Mixed 9 A 44% 37(+/-11) c.(7+1_8-1)_(171+1_172-1)del: hom
c.(171+1_172-1)_(412+1_413-1)del: hom
c.(171+1_172-1)_(534+1_535-1)del: hom
Klein, 2005 Mutational screen 1 n.a. 100% 40 p.Arg275Trp
+ p.Lys211Asn: comp. het.
Clarimon, 2005 Family study 4 JO 50% 24(+/-10) c.(412+1_413-1)_(734+1_735-1)del: hom
Shyu, 2005 Other/Mixed 16 A n.a. 44(+/-8) c.(7+1_8-1)_(171+1_172-1)del: hom
c.(171+1_172-1)_(412+1_413-1)del: hom
c.(734+1_735-1)_(871+1_872-1)del: hom
c.(871+1_872-1)_(933+1_934-1)del: hom
c.(7+1_8-1)_(412+1_413-1)del: hom
c.(171+1_172-1)_(534+1_535-1)del: hom
c.(?_-103-1)_(7+1_8-1)del: hom
 Show more (+4)
Poorkaj, 2005 Mutational screen 2 n.a. 0% 12(+/-5) c.(171+1_172-1)_(412+1_413-1)del
+ p.Pro113Thrfs*51: comp. het.
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